Reports of clinical trials often include adjusted analyses, which incorporate covariate data into the analysis model. Adjusting for covariates can increase the precision of treatment effect estimates and increase the power of statistical tests, without the need to increase sample size. In individually randomised trials, the main reason to adjust for a particular covariate is that it is expected...

In this paper, we propose a new model for designing integrated forward/reverse logistics based on pricing policy in direct and indirect sales channel. The proposed model includes producers, disposal center, distributers and final customers. We assumed that the location of final customers is fixed. First, a deterministic mixed integer linear programming model is developed for integrated logistic...

The paper introduces a new autoregressive model of order one for time seriesof counts. is comprised linear as well bilinear component. These two components are governed by random coefficients. autoregression achieved using the negative binomial thinning operator. method moments and conditional maximum likelihood discussed parameter estimation. practicality presented on real data set.

A mixed-symmetry nuclear shell-model scheme for carrying out calculations in regimes where there is a competition between two or more modes is proposed. A one-dimensional toy model is used to demonstrate the concept. The theory is then applied to 24Mg and 44T i. For lower pf -shell nuclei such as 44−48T i and 48Cr there is strong SU(3) symmetry breaking due to the spin-orbit interaction. Howeve...