Abstract Manual assembly lines productivity is threatened by the increased complexity brought mass customisation demand trends. Industry 4.0 offers potential solutions to address this situation, but methodology implement it still a subject of study. As preliminary step, article aims identify dominant factors affecting Key Performance Indicators mixed-model lines. To do so, parametric and discre...

Abstract Fourth industrial revolution called Industry 4.0 has radically transformed production systems in manufacturing companies by the integration of emerging technologies. However, manufacturers must overcome several barriers, such as lack qualified talent to develop and manage various high-technology systems. Assembly system design aims define proper assembly line configurations with optima...

This article focuses on the Mixed-Model Assembly Line Balancing single-target problem of type 2 with single-sided linear assembly line configurations, which is common in industrial environment small and medium-sized enterprises (SMEs). The main objective to achieve Algorithmic Transparency (AT) when using Genetic Algorithms for resolution balancing operation times. done by means a new matrix me...

Modern aircraft are more integrated with advanced systems functionalities, which result in ever-increasing aircraft complexity, further development difficulties and development delays. These system complexities are mostly in the form of system interactions that make it difficult to understand the overall system characteristics. At the early stages of final assembly line (FAL) design, one of the...

In this paper we consider the problem of designing a mixed assembly–disassembly line for remanufacturing. That is, parts from the disassembly and repair of used products can be used to build “new” products. This is a problem common to many OEM remanufacturers, such as Xerox or Kodak. We study two main configurations, under the assumption that the disassembly sequence is exactly the reverse of t...

This article takes an interest in improving the performance of a subproblem of car sequencing: the resequencing problem. It extends a model of assembly line with the simulation of buffer stocks with drawers. Presequencing and resequencing are modeled with different types of stock management policy. Furthermore, postponement is introduced by two points of differentiation within the line. After c...

Herein, we describe the establishment and characterization of the first mixed-phenotype acute leukemia cell line (JIH-5). The JIH-5 cell line was established from leukemia cells with B lymphoid/myeloid phenotype from a female mixed-phenotype acute leukemia patient. JIH-5 cells exhibit an immunophenotype comprised of myeloid and B lymphoid antigens. Whole-exome sequencing revealed somatic mutati...