The study objective was to elucidate the molecular mechanisms underlying the negative effects of mycophenolic acid (MPA) on human intestinal cells. Effects of MPA exposure and guanosine supplementation on nucleotide concentrations in LS180 cells were assessed using liquid chromatography-mass spectrometry. Proteomics analysis was carried out using stable isotope labeling by amino acids in cell c...

This paper presents findings from shake table experiments on cable-braced and unbraced welded hospital piping systems. The research identifies the capacity characteristics of a hospital piping system with and without bracings as well as the system’s weak points. The system was tested to the ICBO AC156 acceptance criteria for nonstructural components. The input motion of 1g was amplified to almo...

High hydrostatic pressurization is proposed for cheese ripening acceleration. Several treatments were used for accelerating ripening of goat’s milk cheese: 50 MPa / 72 h, 400 MPa / 5 min and 400 MPa / 5 min followed by 50 MPa / 72 h all at 14 °C. Moisture content and pH were higher in 400 MPa treatments compared to the others. By measuring proteolysis indexes, 400 MPa treatments were found to a...

This study describes the seismic assessment of Archangeloi (Başmelekler) Church in Kumyaka (Sige), Türkiye. The is an important religious monument that has survived to present day from eighth century. Through field surveys, structural system, damages and masonry texture were determined. Pushover analysis was performed with OpenSees software, which advanced nonlinear capability. Damage TC3D mate...

Rocking isolation of structures is evolving as an alternative design concept in earthquake engineering. The present paper investigates the seismic performance of an actual overpass bridge of the Attiki Odos motorway (Athens, Greece), employing two different concepts of rocking isolation: (a) rocking of the piers on the foundation (rocking piers); and (b) rocking of the pier and foundation assem...