Mannobiose-modified polyethylenimines (PEI) are used in gene therapy to generate nanoparticles of DNA that can be targeted to the antigen-presenting cells of the immune system. We report that the sugar modification alters the DNA organization within the nanoparticles from homogenous to shell-like packing. The depth-dependent packing of DNA within the nanoparticles was probed using AFM nano-inde...

OBJECTIVE We wanted to evaluate the role of the arterial phase (AP) together with the portal venous phase (PP) scans in the diagnosis of Fitz-Hugh-Curtis syndrome (FHCS) with using computed tomography (CT). MATERIALS AND METHODS Twenty-five patients with FHCS and 25 women presenting with non-specifically diagnosed acute abdominal pain and who underwent biphasic CT examinations were evaluated....

In this paper we establish a general algorithmic framework between bin packing and strip packing, with which we achieve the same asymptotic bounds by applying bin packing algorithms to strip packing. More precisely we obtain the following results: (1) Any offline bin packing algorithm can be applied to strip packing maintaining the same asymptotic worst-case ratio. Thus using FFD (MFFD) as a su...

The polymorphism and solid-state peculiarities of imidazo[1,5-a]pyridine derivatives have been investigated by a theoretical experimental approach to shed light on the structural energetic features. Four couples polymorphs an ionic crystal form reported analysed. Hirshfeld Surface Energy Frameworks used better understand packing features, in comparison with literature structures. collection the...

The vector bin packing problem (VBP) is a generalization of bin packing with multiple constraints. In this problem we are required to pack items, represented by p-dimensional vectors, into as few bins as possible. The multiple-choice vector bin packing (MVBP) is a variant of the VBP in which bins have several types and items have several incarnations. We present an exact method, based on an arc...