Abstract Purpose of Review This article provides a brief and up-to-date overview promising molecular targets novel therapeutic approaches in neuroblastoma (NB). Recent Findings High-risk NB is hard to manage with existing treatment modalities, so more than half those cases are unable achieve long-term survival. With deep understanding pathogenesis, numerous have been discovered, offering wide r...

Approximately 90% of all head and neck malignancies and 94% of oral malignancies are squamous cell carcinoma (SCC). Tobacco smoking is considered as the most important causative agent for SCC. Despite aggressive and multidisciplinary treatment approaches, there has been no significant improvement in 5-year survival over the past 20 years. Several prognostic and predictive clinical, pathological...