In this study, aniline-formaldehyde polymer was synthesized and then modified with extra aniline as cross-linker in the presence and absence of Ni(II) as the template to produce Ion Imprinted Poly(Aniline-Formaldehyde) (IIPAF) and Non Imprinted Poly(Aniline-Formaldehyde)(NIPAF) The IIPAF was subjected to adsorption, preconcentration and determination of Ni(II) ion in envir...

In this study a novel method is described for selective quantization of domperidone in biological matrices applying molecular imprinted polymers (MIPs) as a sample clean up procedure using high performance liquid chromatography coupled with a fluorescence detector. MIPs were synthesized with chloroform as the porogen, ethylene glycol dimethacrylate as the crosslinker, methacrylic acid as the mo...

In this study, a novel method is described for the determination of tramadol in biological fluids using molecularly imprinted solid-phase extraction (MISPE) as the sample clean-up technique combined with high-performance liquid chromatography (HPLC). The water-compatible molecularly imprinted polymers (MIPs) were prepared using methacrylic acid as functional monomer, ethylene glycol dimethacryl...

Molecularly imprinted polymers (MIPs) have been playing an increasingly important role in volatile organic compounds (VOC) sensing for air quality control. The unique feature of these materials is their biomimetic molecular recognition functionality. Theoretical chemistry can advance our ability to design and synthesize new MIPs with specific functions, providing valuable insight into the syste...

Molecularly imprinted polymers (MIPs) are gaining great interest as tailor-made recognition materials for the development of biomimetic sensors. Various approaches have been adopted to interface MIPs with different transducers, including the use of pre-made imprinted particles and the in situ preparation of thin polymer layers directly on transducer surfaces. In this work we functionalized quar...

Within biological systems, these are usually dynamic and are the result of a mass of noncovalent interactions, which act collectively to form a very stable system. Molecular imprinting is a relatively new and rapidly evolving technique used to create synthetic receptors, having recognition properties comparable to the biological systems and it also possesses great potential in a number of appli...

The polymerization of partially methylated β-cyclodextrin (CRYSMEB) with epichlorohydrin was carried out in the presence of a known amount of toluene as imprinting agent. Three different preparations (D1, D2 and D3) of imprinted polymers were obtained and characterized by solid-state (13)C NMR spectroscopy under cross-polarization magic angle spinning (CP-MAS) conditions. The polymers were prep...

Herein we explore phospholipid imprinting as a means to design receptors for complex glycolipids comprising the toxic lipopolysaccharide endotoxin. A series of polymerizable bis-imidazolium and urea hosts were evaluated as cationic and neutral hosts for phosphates and phosphonates, the latter used as mimics of the phospholipid head groups. The bis-imidazolium hosts interacted with the guests in...

We present a previously undescribed initiative and its application, namely the design of molecularly imprinted polymers (MIPs) for producing protein crystals that are essential for determining high-resolution 3D structures of proteins. MIPs, also referred to as "smart materials," are made to contain cavities capable of rebinding protein; thus the fingerprint of the protein created on the polyme...

Molecularly imprinted technology (MIT) has the characteristics of specificity and high selectivity, which is one of the most promising methodologies. Besides, the polymers are made using MIT as the functional material of solid-phase extraction and chromatographic fractionating and sensor, because of the characteristics of the high selectivity, the better stability and easy preparation. This rev...