A DNA-binding affinity and the effect on restriction enzymes activity of seven carbocyclic mono- and bis-lexitropsins and two analogues of pentamidine with unsubstituted N-terminal amine group were investigated. DNA association constants (Kapp) show that DNA affinity of mono-compounds is much weaker than netropsin and distamycin. Bis-analogues of netropsin bind DNA more strongly than mono-ligan...

This paper proposes a way to assess total electric field strength by using mono-axial probe (instead of isotropic, tri-axial probe). When mono-axial probe is used, additional conversion factor should be applied. Consequently, the usage of mono-axial probe causes additional uncertainty in measurement results that should be taken into account. Measurement results for seven different environments ...