leukodystrophies are familial disorders with onset usually in infancy or childhood. the name comes from the greek leuko meaning white and dystrophy meaning imperfect growth or development. leukodystrophy is a progressive, genetic disorder with an autosomal recessive or x-linked mode of inheritance. the clinical features consist of motor dysfunction with varying degrees of cognitive decline. mag...

Parkinson's disease (PD) is a common, progressive and multisystem neurodegenerative disorder characterized by motor and non-motor symptoms. Advanced magnetic resonance imaging, positron emission tomography, and functional magnetic resonance imaging can render the view toward understanding the neural basis of these non-motor syndromes, as they help to understand the underlying pathophysiological...

Introduction. Contemporary research of Parkinson's disease increasingly emphasizes the importance various non-motor signs, including cognitive and language deficits. This is a significant shift from previous which focused primarily on study motor disorders. Objective. article aims to systematically present analyse contemporary empirical data presence deficits in disease. Studies assessment trea...

OBJECTIVE In both clinical practice and research, motor delay is understood to be explained, at least in part, by intellectual abilities; however, no data are available to operationalize these criteria to guide clinical decision making. This study provides data on IQ and motor skills in children to answer 3 research questions concerning the relationship between IQ and motor skill: (1) Can motor...

Knowledge about aging of perceptual-motor skills is based almost exclusively on cross-sectional studies. We examined age-related changes in the retention of mirror-tracing skills in healthy adults who practiced for 3 separate days at baseline and retrained 5 years later at follow-up. Overall, the speed and accuracy of an acquired skill were partially retained after a 5-year interim, although th...