BACKGROUND AND PURPOSE Polyglutamine expansion spinocerebellar ataxias are autosomal dominant slowly progressive neurodegenerative diseases with no current treatment. MR imaging is the best-studied surrogate biomarker candidate for polyglutamine expansion spinocerebellar ataxias, though with conflicting results. We aimed to review quantitative central nervous system MR imaging technique finding...

BACKGROUND AND PURPOSE To use MR spectroscopy to aid in the diagnosis of demyelinating disease and to help differentiate tumefactive demyelinating lesions from neoplastic processes. MATERIALS AND METHODS MR imaging of the brain was obtained in 4 patients who presented clinically with focal neurologic deficits. MR imaging initially revealed parenchymal mass lesions. Single-voxel MR spectroscop...

PURPOSE The aim of this study was to explore the diagnostic effectiveness of magnetic resonance (MR) spectroscopy with diffusion-weighted imaging on the evaluation of the recurrent contrast-enhancing areas at the site of treated gliomas. METHODS AND MATERIALS In 55 patients who had new contrast-enhancing lesions in the vicinity of the previously resected and irradiated high-grade gliomas, two...

Introduction Positron emission tomography is a widely used and established tool for clinical tumour diagnosis and is the gold standard for metabolic imaging. The method complements MR imaging with respect to its metabolic specificity and helps to judge the malignancy and extent of the tumour tissue. Recently, the need to perform two separate scans has been negated through the development of new...