• GWS recovery was observed by 617 monitoring wells in NCP after MRP operation. GRACE detected similar patterns of depletion and with wells. Pumping decrease precipitation increase jointly drove recovery. The South-to-North water diversion Middle Route Project (MRP) is expected to alleviate the long-term groundwater storage (GWS) North China Plain (NCP) beginning its operation December 2014. Th...

In MANET, the multicast routing is considered a non-deterministic polynomial (NP) complexity, it contains assorted objectives and restrictions. issue of quality services (QoS) based upon cost, delay, jitter, bandwidth, are constantly deemed as multi-objective for directing protocols (MR). Conversely, mobile node has finite battery energy lifetime network depends on its energy. Here, MR problem ...

In this paper, we focus on spatial formations when interacting via mobile robotic telepresence (MRP) systems. Previous research has found that those who used a MRP system to make a remote visit (pilot users) tended to use different spatial formations from what is typical in humanhuman interaction. In this paper, we present the results of a study where a pilot user interacted with ten elderly vi...

Intracellular glutathione (GSH) has been implicated as a regulatory determinant of multidrug resistance protein (MRP) function. The objective of the present study was to evaluate in vivo the ability of d,l-buthionine-(S,R)-sulfoximine (d,l-BSO), a potent inhibitor of GSH biosynthesis, to reverse MRP-mediated drug resistance to doxorubicin. Athymic nude mice (nu/nu) bearing advanced parental hum...

CA Corresponding Author Tel: (+55)11 3726 7222, ext. 2165 Fax: (+55)11 3726 1505 E-mail: [email protected] BACKGROUND: We have previously shown that the calcium-binding protein MRP-14 secreted by neutrophils mediates the antinociceptive response in an acute inflammatory model induced by the intraperitoneal injection of glycogen in mice. Aim: In an attempt to broaden the concept that neutrophil...

Pengelolaan bahan baku memiliki peran dalam meningkatkan keuntungan PT XYZ. Kondisi saat ini XYZ dihadapkan terjadi peningkatan permintaan terhadap readymix pada type K 225 akibat sudah dimulainya pembangunan di wilayah Kabupaten Madiun. Peningkatan perlu adanya perencanaan untuk mengatur kebutuhan baku. Pada penelitian menggunakan metode Material Requirement Planning (MRP) Penentuan lot MRP ti...

Objective(s): Crocetin, one of the main substances of saffron extract, has anti-cancer effects. Drug resistance proteins (e.g. MRP1 and MRP2) are important reasons for the failure of cancer therapy. We intended to investigate the efficacy of crocetin on MRP1 and MRP2 activity in human ovarian cisplatin-resistant carcinoma cell line (A2780-RCIS).Materials and Methods: The cytotoxic effect of cro...

Non-P-glycoprotein multidrug resistance of HL60/ADR cells appears to be related to overexpression of the MRP gene. Recent studies suggest that this gene may play an important role in a new form of cell resistance to certain chemotherapeutic agents. To examine mechanisms regulating transcriptional activity of this gene, a 2.2-kilobase 5'-flanking sequence of MRP has been isolated from a genomic ...

RNase MRP is a ribonucleoprotein (RNP) particle which is involved in the processing of pre-rRNA at site A3 in internal transcribed spacer 1. Although RNase MRP has been analysed functionally, the structure and composition of the particle are not well characterized. A genetic screen for mutants which are synthetically lethal (sl) with a temperature-sensitive (ts) mutation in the RNA component of...