In a previous study, we reported that two kaempferol glycosides isolated from Laurus nobilis L., kaempferol-3-O-alpha-L-(2'',4''-di-E-p-coumaroyl)-rhamnoside (C2) and kaempferol-3-O-alpha-L-(2''-E-p-coumaroyl-4''-Z-p-coumaroyl)-rhamnoside (C3), showed strong antibacterial activities against methicillin-resistant Staphylococcus aureus (MRSA) and vancomycin-resistant enterococci. Thereafter we fo...

Staphylococcus aureus is one of the most common causes of nosocomial infections. The purpose of this study was the synthesis and in vitro evaluation of antimicrobial activity of 10 new 3-oxazolidin-2-one analogues on 12 methicillin resistant S. aureus (MRSA) clinical isolates. S. aureus confirmation was achieved via catalase and coagulase test. Molecular characterization of MRSA was performed b...

BACKGROUND Zingiber spectabile, commonly known as Beehive Ginger, is used as an ethnobotanical plant in many countries as an appetizer or to treat stomachache, toothache, muscle sprain, and as a cure for swelling, sores and cuts. This is the first report of isolation of Streptomyces strain from the root of this plant. Strain Universiti Kebangsaan 25 (SUK 25) has a very high activity to produce ...

Infections caused by methicillin-sensitive Staphylococcus aureus (MSSA) and methicillin-resistant S. aureus (MRSA) are prevalent. MRSA infections are difficult to treat and there are no new classes of antibiotics produced to the market to treat infections caused by the resistant bacteria. Therefore, using antibiotic enhancers to rescue existing classes of antibiotics is an attractive strategy. ...

Abstract Methicillin-resistant Staphylococcus aureus (MRSA) and resistant Escherichia coli (r E.coli ) infections can spread rapidly. Further they are associated with high morbidity mortality from treatment failure. Therapy involves multiple rounds of ineffective antibiotics alongside unwanted side effects, alternative treatments crucial. Apple cider vinegar (ACV) is a natural, vegan product th...

Methicillin-resistant Staphylococcus aureus (MRSA) is one of the most prevalent multidrug-resistant pathogens worldwide, exhibiting increasing resistance to the latest antibiotic therapies. Here we show that the triple β-lactam combination meropenem-piperacillin-tazobactam (ME/PI/TZ) acts synergistically and is bactericidal against MRSA subspecies N315 and 72 other clinical MRSA isolates in vit...

Aim: To evaluate the in vitro activity of teicoplanin against clinical methicillin resistant Staphylococcus aureus isolates was the aim of this study Methods and Material: A total of 62 previously confirmed MRSA isolates were included in this study. Susceptibility testing and result interpretation of isolates to teicoplanin was performed by the E test and disk diffusion method as per Clinical a...

BACKGROUND Methicillin-Resistant Staphylococcus aureus (MRSA) are bacteria responsible for several difficult-to-treat infections in humans. These strains have developed, through the process of natural selection. Infections by MRSA are more difficult to treat with standard types of antibiotics and thus more dangerous to human health. OBJECTIVES The aim of this study was to evaluate the bacteri...

BACKGROUND AND THE PURPOSE OF THE STUDY Hospital-acquired methicillin-resistant Staphylococcus aureus (MRSA) has been a major problem worldwide in chemotherapy of infection disease. This study was designed to assess the enhancing effects of a new group of dihydropyridine-3,5dicarboxamides, in combination with cloxacillin with distinctly different mechanisms of action against MRSAs. MATERIAL A...

Abstract The antibacterial activity of crude extract Nigella sative was studied on the some pathogenic bacteria by using paper disc diffusion. tested strains were: Escherichia coli, Enterococcus faecalis, staphylococcus aureus (MRSA) and psendomonas aeruginosa . results were showed that produced inhibition zone in all ranging from (20 mm) S.aureus MRSA (12 P.aureginusa Some Volatile Oils determ...