This paper describes a framework for multimodal categorial systems, i.e. systems that allow different modes of logical behaviour to be displayed within a single system. From a linguistic point of view, this characteristic amounts to making available multiple modes of linguistic description within a single formalism. A key advantage is that when it comes to treating a given phenomenon, the multi...

Numerous nonsurgical interventions have been reported to improve symptoms of knee osteoarthritis (OA) over the short term. However, longer follow-up is required to accurately characterize outcomes such as cost effectiveness and delayed arthroplasty. A total of 553 patients with symptomatic knee OA who previously underwent a single 8-week multimodal treatment program were contacted at 1 year (n ...

Neuroendocrine tumors of the gut, carcinoids have been a diagnostic and therapeutic challenge over the years. The primary diagnostic work-up includes biochemical testing, particularly analysis of chromogranin A and urinary 5-HIAA. The most sensitive localization procedure is somatostatin receptor scintigraphy, which will be supplemented by ultrasonography for liver metastases and concomitant bi...

Pleural malignancies constitute either primary pleural malignancies, such as malignant pleural mesothelioma (MPM), or secondary pleural tumours, either from pleural metastasis or direct extension of adjacent tumours. Mesothelioma is a rare aggressive tumour of the pleural surfaces associated with prior asbestos exposure. Mesothelioma is also a challenging disease from a diagnostic staging, and ...

Bilateral complex regional pain syndrome (CRPS) appears to be unusual [1–5]. We report details of bilateral CRPS diagnosed by International Association for Study of Pain (IASP) criteria in five patients who presented with florid symptoms (more prominent in one extremity) that persisted despite physical therapy (PT) and medications (Figure 1). They were effectively treated with a novel multimoda...

Rectal cancer management improved results in the last thirty-five applying new integrated treatment options. Preoperative radiochemotherapy or radiotherapy alone joined to the modern surgery gaining significant improvement of outcomes. Nevertheless, a definitive conclusion about superiority of one on the other in term of survival and toxicity is still lacking, and further improvement is in gene...

BACKGROUND Sensory distortions of body image commonly occur during migraine, seizures, nondominant cortical infarcts and hallucinogen abuse. METHODS We report the case of a 30-year-old woman with paranoid schizophrenia presenting with postpartum onset multimodal sensory distortions in the absence of any neurological disorders or substance use. RESULTS Her symptoms involved persistent facial...

Optimal perioperative pain control for total joint arthroplasty remains a challenge. Whereas traditional regimens have relied heavily on opioids, newer multimodal pathways are increasingly gaining popularity as safer and more effective alternatives. The main premise of multimodal analgesia is decreased consumption of opioids, and hence lesser opioid-related adverse events. Other reported advant...

The world is multimodal.1 We sense our environments using inputs from multiple sensory modalities. Similarly, digital information is increasingly available through multiple media. In this extended abstract, we present a general computational framework for understanding multimodal learning and perception that builds on the analysis-by-synthesis approach [2, 3]. The analysis-by-synthesis approach...

We conducted an incremental cost-effectiveness analysis to evaluate an adjuvant multimodal therapy (chemotherapy + radiotherapy) in patients with esophageal adenocarcinoma undergoing surgery. We utilized the clinical data of a published controlled trial comparing preoperative chemotherapy + radiotherapy versus surgery alone. Information on costs was derived from local data and verified against ...