Objective. It has been stated that brain cancers are an increasingly serious issue in many parts of the world. The aim of our study was to determine a possible relationship between Vitamin D receptor (VDR) gene polymorphisms and the risk of glioma and meningioma. Methods. We investigated the VDR Taq-I and VDR Fok-I gene polymorphisms in 100 brain cancer patients (including 44 meningioma cases a...

BACKGROUND Cervical lymph node metastases of meningioma represent an important diagnostic and treatment challenge. Not only has this entity been rarely described, but successful treatment has never been reported in the literature. METHODS AND RESULTS This case report was conducted using reviews of the literature. A 58-year-old man with a history of resected anaplastic meningioma was referred ...

INTRODUCTION The co-existence of pituitary adenoma and meningioma is extremely rare. It is even rarer in patients with no previous known risk factors for either tumour. Here, we present a case of synchronous non-functioning pituitary adenoma with suprasellar and olfactory groove meningiomas in a patient without previous irradiation. METHODS The tumours were diagnosed on MRI in the 65-year-old...

Multiple endocrine neoplasia type 1 (MEN1) syndrome includes varying combinations of endocrine and non-endocrine tumors. There are also a considerable number of atypical MEN1 syndrome. In this case, a 68-yr-old woman was referred to the Department of Endocrinology for hypercalcemia. Five years ago, she had diagnosed as primary hyperaldosteronism and now newly diagnosed as parathyroid hyperplasi...

Background: Spinal meningiomas are frequent tumors and they may be associated with other tumors involving central nervous system or other systems, especially in the patients with some syndromes such as neurofibromatosis or multiple endocrine neoplasia. However, spinal angiolipomas are quite rare benign tumors, and they are generally solitary lesions. There is only one case whose spinal angiolip...

Meningiomas with distant metastases rarely occur. We report a patient with coincident primary lung cancer and metastatic meningiomas. The presence of distinct imaging features and a differential response to chemotherapy enabled us to distinguish the primary lung cancer from the metastatic lesions. Previous studies suggest that several factors can enhance the propensity of meningioma for metasta...

PM-11. DEVELOPMENT OF A HUMAN MENINGIOMA MOUSE XENOGRAFT MODEL WITH THE SPONTANEOUSLY IMMORTAL CELL LINE KCI-MENG1 Sharon Michelhaugh1, Anthony Guastella1, KaushikVaradarajan1, Lisa Polin1,2, Aliccia Bollig-Fischer1,2, Fazlul Sarkar1,2, and Sandeep Mittal1,2; Wayne State University, Detroit, MI, USA; Karmanos Cancer Institute, Detroit, MI, USA BACKGROUND: There is a paucity of effective therapi...