background: multiple sclerosis (ms) is a demyelinating disease of the central nervous system and cytokines may play a role in the development of ms lesions. objective: to determine levels of different cytokines in patients with relapsing-remitting ms (rr-ms) compared to healthy controls. methods: profiles of pro-inflammatory, th1-, th2-, and th17-related cytokines were compared by quantitative ...

background: lack of sufficient information on the mechanism of plasma exchange (pe) therapy in multiple sclerosis (ms), has limited this treatment to individual patients with severe relapses who have been refractory to other treatments. this is while pe is used very successfully as a first-line standard treatment in many other neuro-immune disorders. recent data suggest that treg/th17 counterba...

Multiple sclerosis (MS) is an immune-mediated disease of the central nervous system (CNS). This highlydisabling disorder is characterized by a variable clinical course. MS is a heterogeneous disease with acomplex pathology and significant social and economic impact. MS is associated with dysfunction ofparts of the nervous system which results in a range of signs and symptoms, ...

objective(s): regulatory t cells, including cd4+cd25+fox3+ and cd8+cd28- cells play an important role in regulating the balance between immunity and tolerance. since multiple sclerosis is an inflammatory autoimmune disease, regulatory t cells are considered to be involved in its pathogenesis. in this study, we investigated the circulatory numbers of the two mentioned types of regulatory t cells...

how to cite this article: naser moghaddasi a. neuroplasticity in early onset multiple sclerosis. iran j child neurol. 2014autumn;8(4): 80-81.   letter to editor, has not abstract. references boiko a, vorobeychik g, paty d, devonshire v, sadovnick d; neurologists. early onset multiple sclerosis: a longitudinal study. neurology 2002; 59(7):1006-10. inaloo s, haghbin s. multiple sclerosis in child...

background: pain, a common phenomenon in multiple sclerosis (ms) patients, is associated with many symptoms and problems.  to investigation severity and distribution of musculoskeletal pain in ms patients. methods: in this cross-sectional study, 115 members of the mazandaran ms association with confirmed ms were randomly selected to participate in the study. the patients were asked to fill out ...

background: multiple sclerosis (ms) is known to affect essentially the central nervous system; however, peripheral nerve involvement, as an additional cause of disability, has been recently noticed. objectives: this study was aimed to perform detailed electrodiagnostic assessments in ms patients to evaluate peripheral nervous system involvement. materials and methods: a total of eighty ms patie...

multiple sclerosis (ms) is an inflammatory, multifocal, immune-mediated disease of the central nervous system that women are at a higher risk to acquire than men. myxovirus resistance protein a (mxa) is used as a predictive marker of bioactivity of interferon-beta (ifn-β) therapy in ms patients. this study was undertaken in west of iran to investigate gender differences in the expression level ...

abstract background and objective : psychological aspects of chronic diseases has attracted many professionals. because the incidence of sudden and uncontrollable symptoms of many diseases, causing stress and create a variety of negative emotions and mood in patients'. the purpose of this study was to investigate the effectiveness of group reality therapy in reduceing stress, anxiety and depres...

multiple sclerosis (ms) is the most common chronic autoimmune demyelinating disorder of the central nervous system (cns) which preferentially involves young women in early child bearing age. opposite to traditional view emphasized on discouraging female patients from enduring pregnancy, recent investigations showed that pregnancy-related physiological alterations, especially during the third tr...