introduction: the most common manifestation of disturbed neurological function following stroke is motor weakness. muscle weakness has been implicated as a factor underlying deficits in gait performance in subjects who have suffered strokes . the purpose of this study was to investigate the relationship between involved lower extremity isometric muscle strength and two functional tasks: gait ab...

Non-paralytic polio (NPP) is commonly thought to be synonymous with "abortive polio," in which the poliovirus neither entered the CNS nor damaged neurons. Described are two epidemic illness -"The Summer Grippe" and Iceland disease -apparently caused by a low virulence but neuropathic type 2 poliovirus, studies showing that neuronal lesions in the brain and spinal cord and muscle weakness were c...

There are many causes of prolonged postoperative muscle weakness, including drugs, residual anesthetics, cerebrovascular events, electrolyte imbalance, hypothermia, and neuromuscular disease. Neuromuscular diseases are relatively rare, with the most common being myasthenia gravis and Lambert-Eaton myasthenic syndrome (LEMS). We report an unusual case in which a patient who was given a muscle re...

INTRODUCTION Disturbances of eye movements are infrequently encountered in motor neuron diseases (MNDs) or motor neuropathies, and there is no known syndrome that combines progressive muscle weakness with downbeat nystagmus. METHODS To describe the core clinical features of a syndrome of MND associated with downbeat nystagmus, clinical features were collected from 6 patients. RESULTS All pa...

Background: X-linked myotubular myopathy (XLMTM) is caused by mutations in the MTM1 gene, leading to absent or dysfunctional myotubularin, respiratory failure and profound muscle weakness at birth, early death.

Survival from critical illness has improved in recent years, leading to increased attention to the sequelae of such illness. Neuromuscular weakness in the intensive care unit (ICU) is common, persistent, and has significant public health implications. The differential diagnosis of weakness in the ICU is extensive and includes critical illness neuromyopathy. Prolonged immobility and bedrest lead...

A 78-year-old man presented with a 46-year history of slowly progressive muscle weakness. He had a past medical history of hypertension but had no familial history of neuromuscular disorders. He first noticed mild muscle weakness affecting his thigh at the age of 32 when he could not keep up with others during mountain climbing. The proximal muscle weakness worsened gradually to difficulty in c...