INTRODUCTION This study aimed to determine the prevalence of Dupuytren's disease in men and its relationship with work exposure, particularly heavy manual work with and without significant use of vibrating tools, using data from a surveillance program for musculoskeletal disorders. METHOD This cross-sectional study was conducted in France between 2002 and 2005. Dupuytren's disease was diagnos...

BACKGROUND Invasive community-onset staphylococcal disease has emerged worldwide associated with Panton-Valentine leucocidin (PVL) toxin. Whether PVL is pathogenic or an epidemiological marker is unclear. We investigate the role of PVL in disease, colonisation, and clinical outcome. METHODS We searched Medline and Embase for original research reporting the prevalence of PVL genes among Staphy...

Avascular osteonecrosis of femoral head causes severe musculoskeletal disability. There is not standard treatment to cure avascular osteonecrosis. Recently, cell therapy using bone marrow stromal cells has begun for this disease.

The global burden of musculoskeletal disease in low and middle-income countries is large, growing, and neglected. While there is considerable funding for the control of communicable disease, there has been little attention paid to either the prevention or the treatment of orthopaedic problems in developing countries. "Safe Roads" was the theme for World Health Day 2004, and this paper examines ...

Radiofrequency ablation is a well-established treatment tool utilized in musculoskeletal oncology. It is a safe, minimally invasive, and cost-effective treatment for many lesions. Most frequently utilized for treating osteoid osteomas, the technique is also helpful for controlling selected lesions from metastatic bone disease and other benign bone disorders, such as, chondroblastomas and osteob...

Modelling ageing and age-related disease Ilaria Bellantuono, Paul K. Potter* MRC/Arthritis Research—UK Centre for Integrated Research into Musculoskeletal Ageing (CIMA), Academic Unit of Bone Biology, The Mellanby Centre, The University of Shefield, S10 2RX, UK MRC Harwell Institute, Mammalian Genetics Unit, Medical Research Council, Harwell, Oxfordshire, OX11 0RD, UK Drug Discovery Today: Dise...

Tendon rupture is a rare complication that occurs in patients receiving corticosteroid therapy. We report a case of a middle-aged man with mixed connective tissue disease who presented with spontaneous biceps tendon rupture 5 weeks after initiation of high-dose corticosteroid therapy. Musculoskeletal ultrasonography was performed at the clinic and helped to confirm the diagnosis. It is a new im...

The mother of a 3-month old girl presented her daughter for chiropractic care with a medical diagnosis of gastroesophageal reflux disease. Her complaints included frequently interrupted sleep, excessive intestinal gas, frequent vomiting, excessive crying, difficulty breastfeeding, plagiocephaly and torticollis. Previous medical care consisted of Prilosec prescription medication. Notable improve...

Stresses and strains are major factors influencing growth, remodeling and repair of musculoskeletal tissues. Therefore, knowledge of forces and deformation within bones and joints is critical to gain insight into the complex behavior of these tissues during development, aging, and response to injury and disease. Sensors have been used in vivo to measure strains in bone, intraarticular cartilage...