Abstract Background JAK (Janus kinase) inhibitors work by inhibiting the activity of one or more enzyme Janus kinase with a therapeutic application for treatment cancer and inflammatory disorders such as rheumatoid arthritis (RA). We aimed to study impact JAK2 mutation in serum patients on response first line conventional synthetic disease-modifying anti-rheumatic drug (csDMARDS) at 3rd month e...

Introduction Multiple nodes and dwarf mutants in barley are a valuable resource for identifying genes that control shoot branching, vegetative growth development. Methods In this study, physiological, microscopic genetic analysis were conducted to characterize fine-map the underling gene of mutant with Stem Nodes Spikes Dwarf ( msnsd ), which was selected from EMS- 60 Co-treated cv . Edamai 934...

Abstract Isocitrate dehydrogenase (IDH) mutations are common genetic alterations in myeloid disorders, including acute leukemia (AML) and myelodysplastic syndrome (MDS). Epigenetic changes, abnormal histone DNA methylation, have been implicated the pathogenic build-up of hematopoietic progenitors, but it is still unclear whether how IDH themselves affect hematopoiesis. Here, we show that IDH1-m...

Effect of Wild and Mutant Strain Lasiodiplodia Pseudotheobromae Mass Produced on Rice Bran as a Potential Bioherbicide Agents for Weeds under Solid state FermentationAdetunji C. O.a, Oloke J.Kb

Effect of Wild and Mutant Strain Lasiodiplodia Pseudotheobromae Mass Produced on Rice Bran as a Potential Bioherbicide Agents for Weeds under Solid state FermentationAdetunji C. O.a, Oloke J.Kb

Effect of Wild and Mutant Strain Lasiodiplodia Pseudotheobromae Mass Produced on Rice Bran as a Potential Bioherbicide Agents for Weeds under Solid state FermentationAdetunji C. O.a, Oloke J.Kb