Recent molecular studies have suggested that viral myocarditis frequently underlies human congestive cardiomyopathy; however, only moderately sensitive and specific techniques were used. Polymerase chain reaction (PCR) gene amplification is a sensitive, specific technique ideally suited for the diagnosis of viral disease in small tissue samples where low copy numbers of the viral genome may be ...

Viral myocarditis is a common cardiovascular disease, which has greatly threatened human health. However, up to now, the pathogenesis of viral myocarditis has been unclear, which leads to the lack of its effective treatments. To investigate the role of chemokines in pathogenesis of viral myocarditis, mRNA expression for a panel of 19 chemokines detected by RT-PCR in myocardial tissue of BALB/c ...

BACKGROUND There are still discrepancies in the association of enterovirus and myocardial disease, partially due to lack of data on the detection of virus antigens in tissues. It is desirable to localize enteroviral antigens so as to establish a link between the two and to study mechanisms of virus persistence. METHODS AND RESULTS Nineteen fixed explanted or postmortem myocardial samples were...

Many different viruses have been implicated in causing myocarditis, including hepatitis C virus.1 We had a case of hepatitis A infection complicated by myocarditis, which made this patient sick and prolonged his recovery period. His serology was positive for hepatitis A but no biopsy or viral isolation was done. As no other cause for myocarditis was evident, hepatitis A virus was presumed to be...

NViral inifectionis may ox7erload the heart by alterinig pulmonary or systemic vascular resistance, mav iniduce conigeniital malformations, or may invade the mature heart muscle and provoke acute anid possibly chlronic myocarditis. The nature of the associationi of myocarditis vith kniowvn viral infections anid the pathophysiologic effects of myocardial involvenmeit are analyzed. Altlhough vira...

Myocarditis and pericarditis are uncommon complications of human rickettsial, ehrlichial and Bartonella infections. Myocardial inflammation usually occurs in the setting of acute disseminated infection. Organisms associated with myocarditis include: Rickettsia rickettsii, R. conorii, Orientia tsutsugamushi, Coxiella burnetii, Anaplasma phagocytophila (the causative agent of Human Granulocytic E...

Background acute myocarditis (AM) clinical onset can span from subclinical disease to acute heart failure (AHF) ventricular fibrillation (VF) or sudden cardiac death in young adults. Myocarditis can underly the aetiology of other cardiomyopathies (CM) such as dilated CM arrhythmogenic left or right ventricle CM. Aim of the study was to evaluate the relationship between myocardial oedema and lat...

Four cases of acute viral myocarditis were diagnosed within three weeks. The clinical features, electrocardiography, cardiac enzymes and other laboratory investigations are described.

Department of Cardiovascular Medicine First Teaching Hospital Tianjin University of Traditional Chinese Medicine Tianjin, China e-mail: [email protected]

Myocarditis has been described during and after a wide variety of infectious agents: viral, rickettsial, bacterial, protozoal, and metazoal diseases may cause cardiac inflammation. We report a case of toxoplasma myocarditis in a young healthy man.