Carpentier, André, Steven D. Mittelman, Benoı̌t Lamarche, Richard N. Bergman, Adria Giacca, and Gary F. Lewis. Acute enhancement of insulin secretion by FFA in humans is lost with prolonged FFA elevation. Am. J. Physiol. 276 (Endocrinol. Metab. 39): E1055–E1066, 1999.—The in vivo effect of elevated free fatty acids (FFA) on b-cell function in humans remains extremely controversial. We examined, ...