Objective(s): Harmful effects of alcohol on brain function including cognitive phenomena are well known. Damage to gut microbiota is linked to neurological disorders. Evidence indicates that intestinal flora can be strengthened by probiotic bacteria. In this study, we evaluated the effect of probiotics administration on LTP induction in rats receiving ethanol.<em...

Despite greater blood pressure reactivity to acute cardiovascular stressors and a higher prevalence of hypertension in type 2 diabetes (T2D) patients, limited information is available regarding arterial baroreflex (ABR) control in T2D. We hypothesized that ABR control of muscle sympathetic nerve activity (MSNA) and heart rate (HR) are attenuated in T2D patients. Seventeen T2D patients (50 ± 2 y...

A diverse range of accessory proteins regulates the behaviour of most ligand- and voltage-gated ion channels. For glutamate receptor 6 (GluR6) kainate receptors, two unrelated proteins, concanavalin-A (Con-A) and postsynaptic density protein 95 (PSD-95), bind to extra- and intracellular domains, respectively, but are reported to exert similar effects on GluR6 desensitization behaviour. We have ...

Abstract. In this paper we present an object-oriented method for the design, verification and implementation of embedded and distributed real-time systems. The method is called Concurrent Object Net (CON). The CON method is based upon extended statecharts which use specific message links for communication. For simulation and verification corresponding Petri nets are used. A platform abstraction...

To determine the role of endothelin-1 (ET-1) and its receptors in salt-sensitive hypertension induced by sensory nerve degeneration, selective ET(A) antagonist (ABT-627) and ET(B) antagonist (A-192621) were used. Newborn Wistar rats were given vehicle or 50 mg/kg capsaicin subcutaneously on the first and second days of life. After the weaning period, male rats were divided into eight groups, an...

Equine bone blocks have osteogenic effects promoting regeneration with biocompatibility and osteoconductivity capacity. Human dental pulp stem cells (hDPSCs) can differentiate into osteoblasts enhancing biomineralization such scaffolds. Melatonin is able to improve health mediate formation. Collagenated equine were coated ammonia-functionalized graphene-oxide (G-N) at two different concentratio...

The goal of the RaPiD (Recon gurable Pipelined Datapath) architecture is to provide high performance con gurable computing for a range of computationally-intensive applications that demand special-purpose hardware. This is accomplished by mapping the computation into a deep pipeline using a con gurable array of coarse-grained computational units. A key feature of RaPiD is the combination of sta...