Four patients received hyperbaric oxygen therapy (HBOT): Three patients had nonarteritic central retinal artery occlusion (CRAO); a fourth patient had a CRAO in the right eye (OD) and a branch retinal artery occlusion (BRAO) with macular involvement in the left eye (OS) secondary to giant cell arteritis. The first two patients presented with a one-day history of CRAO, the third patient with a 1...

PURPOSE The risk of visual loss after nonocular surgeries is very low, between 0.2% and 4.5%. According to the American Society of Anesthesiologists, ischemic optic neuropathy has been reported mostly after spinal surgery (54.2%), followed by cardiac surgery and radical neck dissection (13.3%). It may occur in association with some conditions that include systemic hypotension, acute blood loss ...

PURPOSE To validate a computerized expert system evaluating visual fields in a prospective clinical trial, the Ischemic Optic Neuropathy Decompression Trial (IONDT). To identify the pattern and within-pattern severity of field defects for study eyes at baseline and 6-month follow-up. DESIGN Humphrey visual field (HVF) change was used as the outcome measure for a prospective, randomized, multi...

Here we report a case of sudden, unilateral, painless visual loss in a middle-aged patient. A 45-year-old gentleman with no known past medical history presented with acute painless left visual impairment. Clinically, he was found to have a left optic neuropathy associated with a swollen and hyperemic left optic disc. The right optic disc was noted to be small and crowded, and both optic discs w...

OBJECTIVE To demonstrate the development of subfoveal fluid associated with optic disc swelling from nonarteritic anterior ischemic optic neuropathy. METHODS Optical coherence tomographic studies obtained during a 3-year period (October 1, 2003, to December 30, 2006) from 76 patients who developed ischemic optic neuropathy from 2 institutions were evaluated. The presence or absence, and the d...

Since the launch in 1998 of the anti-impotence drug sildenafil (viagra), the American food and drug administration has identified 50 cases of drug-related blindness, the so-called nonarteritic anterior ischemic optic neuropathy. This, very serious, side effect frequently leads to sudden, mostly irreversible loss of vision, and there is no proven effective treatment to cure patients or to preven...

BACKGROUND Proliferative diabetic retinopathy leading to vitreous hemorrhage, tractional retinal detachment, and neovascular glaucoma is a major cause of severe sight impairment in adults of working age worldwide. Neovascular glaucoma occurs in 2.5% of patients with proliferative diabetic retinopathy, which is difficult to treat and often leads to blindness. Onset of neovascular glaucoma with r...

Obesity hypoventilation syndrome (OHS) is defined as obesity (body mass index, >30 kg/m2) with daytime hypoventilation (PCO2, >45 mmHg) that is not secondary to cardiopulmonary or neurologic disease. Around 80–90% of the patients with OHS have obstructive sleep apnea and severe arterial oxygen desaturation. Obstructive sleep apnea has been found to be associated with a variety of eye diseases, ...

Venous thrombosis aVects one in 1000 individuals per year 2 causing significant morbidity and mortality. Inherited thrombophilia is a genetically determined tendency to thrombosis. Dominant abnormalities or combinations of mutations of varying penetrance giving rise to less severe defects may be suspected clinically from evidence of early age of onset, frequent recurrence, or family history. Mi...

PURPOSE To investigate whether optic disc size is related to retinal venule and arteriole diameters. METHODS The population of Beaver Dam, Wisconsin, aged 43 to 86 years were invited to participate in a baseline examination from 1988 to 1990. During this examination, photographs, centered on the optic discs, were taken after pupil dilation. Optic discs and cups were measured from stereoscopic...