Before going to the gym for a workout or after indulging in cake at the office party, people with diabetes can use a portable monitor to take a quick blood glucose measurement and adjust their food or insulin intake to prevent extreme dips or spikes in blood sugar. The inexpensive finger-prick testing devices that allow diabetics to check their glucose levels throughout the day may sound like s...

Nanotechnology is an emerging technology seeking to exploit distinct technological advances of controlling the structure of materials at a reduced dimensional scale approaching individual molecules and their organised aggregates or supramolecular structures. These technological innovations, referred to as nanomedicines by the National Institutes of Health (Bethesda, MD, USA), have the potential...

Although mentions of nanoparticles in relation to biomedicine appeared in the late 1970s and are now the subject of over 10,000 publications per year, the term “Nanomedicine” only appeared at the turn of this century, and less than 30 papers including this term were published up to 2005. Ten years later, Web of Science indicates the publication of more than 1000 Nanomedicine articles in 2015 am...

Baran Sumer1, Jinming Gao2† †Author for correspondence 1Department of Otolaryngology, Head and Neck Surgery, UT Southwestern Medical Center, 5323 Harry Hines Blvd., Dallas, TX 75390, USA Tel.: +1 214 648 3102; Fax: +1 214 648 2246; E-mail: baran.sumer@ utsouthwestern.edu 2Department of Pharmacology, Harold C Simmons Comprehensive Cancer Center, University of Texas Southwestern Medical Center, 5...

To date, numerous inorganic nanocarriers have been explored for drug delivery systems (DDSs). However, the clinical application of inorganic formulations has often been hindered by their toxicity and failure to biodegrade. We describe here a transformable liquid-metal nanomedicine, based on a core-shell nanosphere composed of a liquid-phase eutectic gallium-indium core and a thiolated polymeric...

BACKGROUND Despite marked optimism in the field of nanomedicine about the use of drug-delivery nanocarriers, uncertainties exist concerning nanocarriers' possible unintended impacts and effects. These uncertainties could affect user acceptance and acceptability. "Acceptance" refers to the intention to put a technology or a device to a specified use. "Acceptability" refers to a value judgment th...

The focus on nanotechnology in cancer treatment and diagnosis has intensified due to the serious side effects caused by anticancer agents as a result of their cytotoxic actions on normal cells. This nonspecific action of chemotherapy has awakened a need for formulations capable of definitive targeting with enhanced tumor-killing. Nanooncology, the application of nanobiotechnology to the managem...