for the first time lactic acid was applied as an efficient and green catalyst for the one-pot three-component synthesis of amidoalkyl naphthols via the condensation between arylaldehydes, 2-naphthol and amides or urea under thermal solvent-free conditions in good to excellent yields. we have demonestrated a mild and efficient eco-friendly tandem synthesis of amidoalkyl naphthols using lactic ac...

a green and convenient méthode for the synthesis of  a variety of xanthene derivatives by condensation reaction between aldehydes and β-naphthol or dimedone in an micellar solution of sodium dodecylphosphonate is described. this method offers several advantages, such as using of a cheap and environmentally benign reaction media, low loadings of sodium dodecylphosphonate as catalyst and easy wor...

Silica tungstic acid (STA) has been found to be an efficient and reusable solid acid catalyst for the synthesis of 2-amino-4H-chromenes via the three-component reaction of aromatic aldehydes, malononitrile, and β-naphthol. STA as a novel solid acid was characterized by X-ray fluorescence, X-ray diffraction, and Fourier transform infrared spectroscopy.

In the title compound, C(38)H(26)O(4), two cinnamo-yloxy groups are linked in a trans fashion to the two O atoms of optically active (R)-1,10-bi-2-naphthol. The dihedral angle between the mean planes of the two naphthyl groups is 71.8 (1)°. The crystal structure contains inter-molecular C-H⋯O and C-H⋯π inter-actions.

The contribution of aliphatic-rich plant biopolymer to sorption of hydrophobic organic compounds is significantly important because of their preservation and accumulation in the soil environment, but sorption mechanism is still not fully understood. In this study, sorption of 1-naphthol by plant cuticular fractions was examined to better understand the contributions of respective fraction. Towa...

Uridine diphosphate glucuronosyltransferases (UGTs) catalyze the glucuronidation of a wide range of xenobiotics and endogenous substrates. However, there is a lack of information concerning the response of human UGTs to inducers, and this observation prompted the current investigation. The glucuronidation of estradiol (3- and 17-positions), naphthol, propofol, and morphine (3- and 6-positions) ...

Aromatic amines are oxidized in animal tissues to oand p-aminophenols, which are rapidly conjugated to give either sulphates or glucosiduronates. Some of the carcinogenic aromatic amines appear to produce their biological effects after conversion into o-aminophenols. 2-Naphthylamine, for example, which produces bladder cancer, is oxidized to 2-amino-6-naphthol and 2-amino-inaphthol by liver sli...

This study was designed to investigate the relationship between environmental exposure to polycyclic aromatic hydrocarbons (PAHs) and oxidative stress, and to evaluate the effects of cigarette smoking and the genetic polymorphisms of CYP1A1, CYP2E1, GSTM1, NAT2 and UGT1A6 on the relationship. The subjects of this study were 105 healthy Korean males without occupational exposure to PAHs. The 8-h...