It may sound a little nutty, but your friends are partially correct. Nutmeg, a spice commonly used to flavor lattes, sweets, and other foods has also been reported to produce a high that is similar to the one obtained with marijuana. Originating from the Myristica fragans tree in Indonesia, the seed is now grown and used globally, mostly for cooking but sometimes as a narcotic. However, for the...

background: despite the development of pediatric post-operative pain management and use of analgesic/narcotic drugs, post-operative pain remains as a common problem. some studies suggested, the most effective approach to controlling immediate post-operative pain may include a combination of drug agents and non-drug methods. the aim of this study was to investigate the effect of music therapy on...

In patients undergoing spine surgery postoperative pain management can often be complicated with side effects associated with high dose narcotic such as respiratory depression and those associated with non-steroidal anti-inflammatory drugs such as interference with bone healing process. Local anesthetics can help in both decreasing postoperative pain and minimizing side effects associated with ...

An association between non-opioid analgesic agents and chronic kidney disease has long been suspected. The presumed development of chronic renal impairment following protracted excessive use of non-opioid analgesia is known as analgesic nephropathy. Many accept analgesic nephropathy as a real entity despite a paucity of robust scientific evidence. The weight of available observational literatur...

(1919-1923), as models of wise policy and sensible treatment. They can, and should, function as beacons for contemporary reformers. I have a few quarrels with Professor Trebach. I do not think that the British experience with narcotic drugs is as applicable to-America as he does. And I think that his view of the past tends to be too narrowly legal. But these are minor reservations about a splen...

A case is reported of narcotic coma in a female lasting 36 hours as a result of deliberate ingestion of 250 ml of halothane. Aspiration of gastric contents led to cardiac arrest which was successfully treated. Artificial ventilation was needed. Halothane hepatitis did not develop despite prolonged episodes of respiratory and circulatory failure and medication with drugs known to interfere with ...

OBJECTIVE To document the management of and outcomes for patients receiving narcotic replacement and tapering with long-acting morphine preparations during pregnancy. DESIGN A prospective cohort study over 18 months. SETTING Northwestern Ontario. PARTICIPANTS All 600 births at Meno Ya Win Health Centre in Sioux Lookout, Ont, from January 1, 2012, to June 30, 2013, including 166 narcotic-e...

The objective of this study was to identify predictors of narcotic analgesic use during medical abortion. Two-thousand-seven-hundredforty-seven women with pregnancies of 63 days gestational age or less received 200 mg mifepristone followed by at-home use of 800 mg vaginal misoprostol in two consecutive clinical trials in the United States, and also reported their use of analgesics. Overall, 79%...

The number of candidate molecules for new non-narcotic analgesics is extremely limited. Here, we report the identification thiowurtzine, a potent analgesic molecule with promising application in chronic pain treatment. We describe chemical synthesis this unique compound derived from hexaazaisowurtzitane (CL-20) explosive molecule. Then, use animal experiments to assess its activity vivo upon ch...