BACKGROUND The purpose of this observational study was to investigate the relationship between upper-airway configuration assessed by CT imaging during the Müller maneuver state and the severity of obstructive sleep apnea syndrome (OSAS). METHODS A total of 358 snoring subjects who underwent standard polysomnography and upper-airway configuration by using CT imaging were enrolled. According t...

Streptococcus pneumoniae is an opportunistic pathogen that colonizes the nasopharynx. Herein we show that carbon availability is distinct between the nasopharynx and bloodstream of adult humans: glucose is absent from the nasopharynx, whereas galactose is abundant. We demonstrate that pneumococcal neuraminidase A (NanA), which cleaves terminal sialic acid residues from host glycoproteins, expos...

Sarcoidosis is a systemic granulomatous disease that usually has a pulmonary presentation. The extrapulmonary organs most frequently affected are lymph nodes, eyes and skin. Rhinopharyngeal involvement is extremely rare. We describe a case of sarcoidosis which was diagnosed through its location in the nasopharynx.

A 70-year-old man fell from a horse and landed on his head. He did not lose consciousness, but immediately noticed a slight change in the tone of his voice and was able to continue his normal activity. Later that day he noticed increasing swelling of his neck with associated dysphagia. He went to his local hospital Casualty Department and was referred to the Otorhinolaryngology Service after ha...

Nasopharyngeal carcinoma is the predominant tumor type arising in the nasopharynx with cervical lymph nodes present in 60-90% of all cases at the time of presentation. The most frequent pathological varieties include squamous cell carcinoma well-differentiated keratinizing, moderately differentiated non-keratinizing and an undifferentiated type. We present a case of non-keratinizing undifferent...

Nasopharyngeal carcinoma (NPC) is distinct from other cancers of the head and neck in biology, epidemiology, histology, natural history, and response to treatment. Radiation therapy is an essential component of curative-intent of non-disseminated disease and the association of chemotherapy improves the rates of survival. In the case of metastatic disease stages, treatment requires platinum/gemc...

This study describes the endoscopic findings about the size of the adenoid tissue and the condition of the nasopharyngeal orifice of the eustachian tube. Results confirmed that only fiberscopic examination allows a thorough inspection of the nasopharyngeal anatomy to make a correct diagnosis and design therapeutic planning. When the presence of adenoid hypertrophy resulting in nasal obstruction...

BACKGROUND Methicillin-resistant Staphylococcus aureus (MRSA) is recognized as a cause of nosocomial infections in both human and veterinary medicine. Studies that examine the nasopharynx and guttural pouches of the horse as carriage sites for MRSA have not been reported. HYPOTHESIS/OBJECTIVE MRSA colonizes the nasopharynx and guttural pouch of horses. To determine the prevalence of MRSA in e...