Many mathematical models have been published with the purpose of explaining aspects of T-cell development in the thymus. In this manuscript we adapted a four-compartment model of the thymus and used a range of mathematical approaches with the aim of explaining the dynamics of the four main thymocyte populations in the mouse thymus, from the emergence of the first fetal thymocyte until the death...

Dispersal is a life-history trait affecting dynamics and persistence of populations; it evolves under various known selective pressures. Theoretical studies on dispersal typically assume 'natal dispersal', where individuals emigrate right after birth. But emigration may also occur during a later moment within a reproductive season ('breeding dispersal'). For example, some female butterflies fir...

Understanding dispersal and habitat selection behaviours is central to many problems in ecology, evolution and conservation. One factor often hypothesized to influence habitat selection by dispersers is the natal environment experienced by juveniles. Nonetheless, evidence for the effect of natal environment on dispersing, wild vertebrates remains limited. Using 18 years of nesting and mark-resi...

During natal dispersal, young animals leave their natal area and search for a new area to live. In species in which individuals inhabit different types of habitat, experience with a natal habitat may increase the probability that a disperser will select the same type of habitat post-dispersal (natal habitat preference induction or NHPI). Despite considerable interest in the ecological and the e...

The functions of the TAF subunits of mammalian TFIID in physiological processes remain poorly characterised. In this study, we describe a novel function of TAFs in directing genomic occupancy of a transcriptional activator. Using liver-specific inactivation in mice, we show that the TAF4 subunit of TFIID is required for post-natal hepatocyte maturation. TAF4 promotes pre-initiation complex (PIC...

1. Hargreaves K. Rediscovery of An funestus in KwaZulu-Natal. Minutes of the KwaZulu-Natal Malaria Meeting, Richard’s Bay, 18-20 September 2000. 2. Barnes K. Malaria Advisory Group. Malaria in KwaZulu-Natal. Guidelines for the Diagnosis and Treatment of Uncomplicated Falciparum Malaria in KwaZulu. Falcon Press, 2001. 3. Bredenkamp BLF, Sharp BL, Mthembu SD, Durrheim DN, Barnes KI. Failure of su...

Resumen El artículo pone en contexto el papel de la mujer mexicana trabajo, reconociendo los avances legales y su realidad ámbito laboral, haciendo énfasis propio vulnerabilidad general que presenta un país cuyo acceso a trabajo digno resulta complejo, lo si mismo dificulta inserción aún más permanencia trabajo. Se análisis las diversas disposiciones tanto Constitución Mexicana, como leyes regl...

BACKGROUND Most studies of the associations between pre-natal or post-natal growth and cognitive ability have been based on children with pathologically slow growth measured between two time points only, rather than children with normal growth trajectories estimated from multiple measures of growth. METHODS We investigated the associations of pre-natal and post-natal trajectories in both weig...

BACKGROUND Available evidence suggests that the low use of antenatal, delivery, and post-natal services by Nigerian women may be due to their perceptions of low quality of care in health facilities. This study investigated the perceptions of women regarding their satisfaction with the maternity services offered in secondary and tertiary hospitals in Nigeria. METHODS Five focus group discussio...

Background To evaluate the association between home-based neonatal care interventions and incidence of maternal health conditions as well to estimate longitudinal trend over 13 years in 39 villages field program area from rural Gadchiroli, India. Methods This was a before-after comparative analysis implemented thirty-nine The newborn were incrementally introduced during trial (1995 – 1998) cont...