premature rupture of membrane (prom) is one of the complications of pregnancy which is blamed for increasing the rate of cesarean. therefore, we studied pregnant women who were admitted in shariati hospital during march 1996 and march 2000, to determine the rate of cesarean delivery in cases with prom after 36th week of pregnancy (term prom). in a retrospective study, we included pregnant women...

Although oral delivery has become a widely accepted route of administration of therapeutic drugs, the gastrointestinal tract presents several formidable barriers to drug delivery. Colonic drug delivery has gained increased importance not just for the delivery of the drugs for the treatment of local diseases associated with the colon but also for its potential for the delivery of proteins and th...

objective: this study investigated the efficacy of bupivacaine wound infusion for pain control and opioid sparing effect after cesarean delivery. materials and methods: we conducted a randomized double blind, placebo controlled clinical trial on 60 parturients undergoing cesarean section at a university hospital in tehran. patients were randomized to receive a pump infusion system that was fill...

Neurodegeneration characterizes pathologic conditions, ranging from Alzheimer's disease to glaucoma, with devastating social and economic effects. It is a complex process implicating a series of molecular and cellular events, such as oxidative stress, mitochondrial dysfunction, protein misfolding, excitotoxicity and inflammation. Natural compounds, because of their broad spectrum of pharmacolog...

A mesoporous silica nanoparticle-based intracellular cysteine delivery system that could be induced and regulated by cell-produced natural antioxidants was synthesized.

The first reported delivery following a natural cycle ICSI in Ireland is described. This technique has the potential to provide successful treatment for a selected group of patients.