The case of a one-year-old girl with necrotizing vulvar infection is presented. appropriate approach for these cases also discussed.

Necrotizing fasciitis(NF) is an extreme form of soft tissue infections. Historically, it has a terrible reputation and still can have an ominous clinical presentation in modern days. Until the twentieth Century, it was responsible for hundreds of thousands of severe infections, disfiguring mutilations, and horrible deaths.Thankfully the incidence of necrotizing fasciitis has dramatically gone w...

Methicillin-resistant Staphylococcus aureus (MRSA) is a rarely reported cause of necrotizing fasciitis. We report an unusually severe case of MRSA necrotizing fasciitis in a previously undiagnosed AIDS patient. Molecular analysis revealed that the strain had the USA300/spa1 genotype, now an abundant cause of community-acquired MRSA infection.

Monomicrobial necrotizing fasciitis (type II) is typically caused by group A streptococcus alone or in combination with Staphylococcus aureus. Escherichia coli has been isolated from polymicrobial or Fournier's gangrene but has rarely been reported in monomicrobial necrotizing fasciitis. We describe the clinical characteristics and outcomes of seven cases of monomicrobial E. coli necrotizing fa...

INTRODUCTION Acute appendicitis is one of the most common surgical diseases, but perforated appendicitis resulting in necrotizing fasciitis of the abdominal wall is exceedingly rare. PRESENTATION OF CASE A 71-year-old male presented to the emergency department with one week of severe right-sided abdominal pain. He was hypothermic, hypotensive, and tachycardic. His abdomen was distended, with ...

Necrotizing soft tissue infections are a group of highly lethal infections that typically occur after trauma or surgery. Many individual infectious entities have been described, but they all have similar pathophysiologies, clinical features, and treatment approaches. The essentials of successful treatment include early diagnosis, aggressive surgical debridement, antibiotics, and supportive inte...

I T is now thirty years since the dental profession was confronted with acute necrotizing periodontal disease as a major health problem from the stand­ point of incidence and wide distribution among the population, both military and civilian. The American soldier of World War I named the disease “ trench mouth.” It previously had been desig­ nated by the eponyms “Vincent’s infec­ tion” and “ Pl...

BACKGROUND AND OBJECTIVES This study examined kidney biopsies with focal segmental glomerular fibrinoid necrosis to identify early features of pauci-immune necrotizing GN and the primary effector cells mediating initial capillary injury. DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS Seventeen consecutive kidney biopsies with focal pauci-immune necrotizing GN, obtained over a 6-year period (20...

OBJECTIVE The goal was to investigate the efficacy of orally administered probiotics in preventing necrotizing enterocolitis for very low birth weight preterm infants. METHODS A prospective, blinded, randomized, multicenter controlled trial was conducted at 7 NICUs in Taiwan, to evaluate the beneficial effects of probiotics in necrotizing enterocolitis among very low birth weight infants (bir...