To ascertain the efficacy of systemic cyclosporin therapy in the management of scleritis we performed an open, uncontrolled study of the use of this drug in severe refractory disease. Five of seven patients whose disease had previously been poorly controlled with a combination of corticosteroids and immunosuppressive drugs responded to cyclosporin therapy (10 mg/kg/day). Systemic side effects o...

CASE REPORT We present the case of a 26 year-old Pakistani male, who after the presumptive diagnosis of anterior tuberculous scleritis (by an atypical clinical appearance and positive epidemiological link), was diagnosed with pulmonary tuberculosis. DISCUSSION Nodular anterior scleritis is an uncommon presentation of tuberculosis (TB). It is considered a diagnostic challenge because of the di...

CASE REPORT A 30-year-old man was referred to our ocular oncology service with a diagnosis of amelanotic choroidal melanoma of the left eye. The following tests were performed: ophthalmoscopy, fluorescein angiography, indocyanine green angiography, ultrasonography, magnetic resonance imaging and biopsy. DISCUSSION The diagnosis of giant nodular posterior scleritis, as suggested by ultrasonogr...

The onset of bilateral necrotising scleritis and marginal corneal ulceration after cataract surgery are described in a patient with diffuse vasculitis syndrome. The finding of immune complexes in this patient's tissue biopsy suggests that they are the cause of a localised primary vasculitis triggered by surgical inflammation. Clinically, this patient's marginal corneal ulceration preceded the s...

necrotizing fasciitis is a part of a spectrum of necrotizing soft tissue infections that usually follow a surgical intervention or a chronic / acute medical illness. diagnosis is often based on symptoms which classically start within hours after an injury. there are no reports on the use of pet/ct in this condition. sparing reports of its association in patients with malignancy (ca of colon and...

PURPOSE Suppressors of cytokine signaling (SOCS) proteins regulate the intensity and duration of cytokine signals and defective expression of SOCS1 and SOCS3 has been reported in a number of human diseases. The purpose of this study was to investigate the role of SOCS1 in intraocular inflammatory diseases (uveitis) and whether SOCS1 expression is defective in patients with ocular inflammatory d...