Triple-negative breast cancer (TNBC) is defined by a lack of expression of both estrogen and progesterone receptor as well as human epidermal growth factor receptor 2. It is characterized by distinct molecular, histological and clinical features including a particularly unfavorable prognosis despite increased sensitivity to standard cytotoxic chemotherapy regimens. TNBC is highly though not com...

In this paper, we investigate some properties of eigenvalues and eigenfunctions of boundary value problems with separated boundary conditions. Also, we obtain formal series solutions for some partial differential equations associated with the second order differential equation, and study necessary and sufficient conditions for the negative and positive eigenvalues of the boundary value problem....

conclusions this study indicates that 2.9% of hemodialysis patients had obi, which is considered as a major public health problem worldwide. moreover, we observed three mutations in s region, including t127p, p153l, and f170s, which caused obi. this study is first to report a mutation analysis of hbv in hemodialysis patients in southwestern iran. these results indicate that current screening te...

Sodium channels in nodal membrane modified by a synthetic analog of batrachotoxin, 7,8-dihydrobatrachotoxinin A-20a-benzoate, were studied under voltage clamp conditions. The voltage dependence of channel activation was shifted by 70—80 mV towards more negative potentials. Selectivity sequence determined from peak current reversal potenial was as follows: Na:NH 4 :K = 1:0.46:0.23. Our data sugg...