BACKGROUND Increasing the living-donor pool by accepting donors with an isolated medical abnormality (IMA) can significantly decrease the huge gap between limited supply and rising demand for organs. There is a wide range of variation among different centres in dealing with these categories of donors. We reviewed studies discussing living kidney donors with IMA, including greater age, obesity, ...

INTRODUCTION Noncontrast CT is the standard of care to evaluate nephrolithiasis. We evaluated the performance of low-dose CT (LDCT) scan for evaluation of renal colic in the emergency room (ER). MATERIALS AND METHODS Patients visiting the ER with suspected nephrolithiasis received a standard-dose CT (SDCT) and an LDCT. Two urologists read the LDCTs and later they read SDCTs. Stone information...

BACKGROUND It is said that renal transplantation lithiasis is rare. However, literature has some different frequencies in this field and most of the studies related to this issue are case reports. Also the exact effect of this complication on the graft survival rate is not clear. OBJECTIVES To determine the prevalence of nephrolithiasis among kidney transplant recipients and evaluate its asso...

objective(s): the aim of study was to determine history of genitourinary diseases in war related bilateral lower limb amputees who were injured during iran-iraq war (1980-1988).   methods: subjects with war related bilateral lower limb amputation (335 persons) were examined by two physicians for any history of genitourinary diseases and their documents were reviewed.   results: the mean age was...

The increasing global prevalence of nephrolithiasis continues to burden the healthcare delivery systems of industrialized nations and exact a disproportionate humanitarian toll on populations of the developing world (1). In the United States alone, the prevalence of nephrolithiasis is nearly twice the rate reported in the 1960s (2-5). The subsequent rise in surgical interventions for nephrolith...

Dent disease (DD) is a rare X-linked recessive renal tubulopathy characterised by low-molecular-weight proteinuria (LMWP), hypercalciuria, nephrocalcinosis and/or nephrolithiasis. DD is caused by mutations in both the CLCN5 and OCRL genes. CLCN5 encodes the electrogenic chloride/proton exchanger ClC-5 which is involved in the tubular reabsorption of albumin and LMW proteins, OCRL encodes the in...

Calcium-containing renal calculi are the most common stone type in reported series and recur in 26–53% of patients over a 10 year period. Because of this tendency, interventions aimed at reducing or preventing recurrence are an important strategy for reducing the morbidity associated with stone disease. This guideline uses an evidence-based review of the published literature with the purpose of...

Nephrolithiasis is a major public health problem with a complex and varied etiology. Most stones are composed of calcium oxalate (CaOx), with dietary excess a risk factor. Because of complexity of mammalian system, the details of stone formation remain to be understood. Here we have developed a nephrolithiasis model using the genetic model Drosophila melanogaster, which has a simple, transparen...

Dent’s disease (MIM #300009) is a rare X-linked disorder characterized by various degrees of proximal tubular (PT) dysfunction, nephrocalcinosis and nephrolithiasis. The exact prevalence is unknown. The disease was first reported by Dent and Friedman, who described two males with vitamin D resistant rickets, hypercalciuria and low molecular weight proteinuria (LMWP) (Dent & Friedman, 1964). Bas...