introduction: it is clear that the proliferation, migration and differentiation processes of embryonic fetal neural tissue are dependent on special trophic factors. these factors are absent or lessl seen in adult tissue. in this research the effects of fetal brain extract (fbe) on the regenerational processes of lesioned prepheral nerve were investigated. materials and methods: the facial nerve...

Traumatic injuries resulting in peripheral nerve lesions often require a graft to bridge the gap. Although autologous nerve auto-graft is still the first-choice strategy in reconstructions, it has the severe disadvantage of the sacrifice of a functional nerve. Cell transplantation in a bioartificial conduit is an alternative strategy to create a favourable environment for nerve regeneration. We...

The relationship between the anatomy and neurochemistry of neurons in the ventral medulla oblongata in regions that is responsible for cardiovascular, airways, and respiratory regulation was investigated. Microinjections of excitant amino acid (glutamate, 100 nl, 100 mM) were made throughout the ventral medulla in anesthetized rats. Arterial blood pressure, sympathetic nerve activity and phreni...

We report that the most common retinal ganglion cell type that remains after optic nerve transection is the M1 melanopsin ganglion cell. M1 ganglion cells are members of the intrinsically photosensitive retinal ganglion cell population that mediates non-image-forming vision, comprising ∼2.5% of all ganglion cells in the rat retina. In the present study, M1 ganglion cells comprised 1.7±1%, 28±14...

The regulative effects of microRNAs (miRNAs) on responses of Schwann cells to a nerve injury stimulus are not yet clear. In this study, we noted that the expression of eight miRNAs was downregulated at different time points following rat sciatic nerve transection, and found that 368 potential targets of these eight miRNAs were mainly involved in phenotypic modulation of Schwann cells. Of these ...

conclusions complete rupture of the facial nerve is challenging and the treatment is surgery, which requires careful planning. introduction facial paralysis is a devastating condition with profound functional, aesthetic and psychosocial consequences. tumors within or outside the skull, bell’s palsy and trauma are the most common causes of facial paralysis in adults. case presentation our patien...

conclusions immediate repair of the facial nerve injury will improve the process of recovery and rehabilitation of the face and forehead muscles and may play a very important role in the patient’s mental satisfaction and improve their quality of life. introduction facial paralysis is common following accidents, trauma, viral infection or tumors. case presentation a 24-year-old male patient was ...

Background: Schwannoma is a peripheral nerve sheath tumor originating from schwann cells. It is the most common neurogenic tumor of the posterior mediastinum. Pleural effusion is a rare presentation of benign schwannoma and it is mainly related to malignant tumors. Histologically, schwannoma as well as solitary fibrous tumor should be considered as a differential diagnosis of spindle cell lesio...