A malignant peripheral nerve-sheath tumour developed in the right S1 nerve root in a man aged 30 causing back pain and sciatica. CT and MRI revealed a destructive tumour of the sacrum invading the retroperitoneal space. The tumour was not resectable with an adequate margin. Chemotherapy, consisting of high-dose ifosfamide followed by a combination of vincristine, doxorubicin and cyclophosphamid...

Both optic nerves were obtained at autopsy from a 28-year-old man with a 2 year history of idiopathic intracranial hypertension who had undergone bilateral optic nerve sheath decompression 14 days before death. Histopathological and ultrastructural examination of the tissue revealed fibroblasts localised to the sites of fenestration. Adipose tissue was also adherent to the optic nerve pia in ar...

A schwannoma, also known as an acoustic neuroma, is a benign nerve sheath tumor composed of schwann cells, which normally produce the insulating myelin sheath covering the peripheral nerves. Schwannoma, originating from the cervical vagus nerve, is an extremely rare neoplasm that usually occurs in men between the 3rd and 6th decades of life. The most common presentation is a painless, slow-grow...

SUMMARY We report the CT and MR imaging findings in a patient with malignant peripheral nerve sheath tumor in the right nasolabial area, which exhibited typical imaging features of cystic adenoid carcinoma.

schwannoma is a benign encapsulated slow-growing tumor that originates from schwann cells of the peripheral nerve sheath. it usually occurs in the head and neck; however, it is rare in the oral cavity. the tongue is the most common site of intraoral schwannomas, followed by the floor of the mouth, palate, gingiva, vestibular mucosa, lips and mental nerve area. we report a rare case of schwannom...

Protein synthesis in the nerve sheath of injured as well as intact mature and developing sciatic nerves from rat and rabbit was investigated by incubating segments of nerve with [35S]methionine in vitro. The composition of labeled proteins under the different conditions of nerve growth was analyzed by two-dimensional gel electrophoresis and fluorography. The expression of six secreted proteins ...

BACKGROUND AND OBJECTIVE To determine whether 6.45-microm free electron laser (FEL) energy can successfully perform optic nerve sheath fenestration and to compare the acute and chronic cellular responses with this surgery. STUDY DESIGN/MATERIALS AND METHODS Optic nerve sheath fenestration was performed in rabbits by using either FEL energy (< 2.5 mJ, 10 Hz, 325-microm spot size) or a knife. T...

A case is reported of an optic nerve glioma with a marked degree of arachnoid hyperplasia which was initially diagnosed as an optic nerve meningioma. Hyperplasia of the arachnoid was also the underlying cause for expansion of the optic canal. The relationship between arachnoid hyperplasia in optic nerve glioma and meningioma of the optic nerve sheath in childhood is discussed.