The purpose of this study was to characterize the Night Eating Syndrome (NES) and its correlates among non-obese persons with NES, and to compare them to non-obese healthy controls. Nineteen non-obese persons with NES were compared to 22 non-obese controls on seven-day, 24-hour prospective food and sleep diaries, the Eating Disorder Examination and the Structured Clinical Interview for DSM-IV D...

PURPOSE People with non-epileptic seizures (NES) consistently report poorer Health-Related Quality of Life (HRQoL) than people with epilepsy. Yet, unlike in epilepsy, knowledge of how social factors influence the HRQoL of adults with NES is limited. To add to the evidence base, this study explores the relationship between HRQoL and perceived stigma among adults with NES, and the role of socio-d...

The effects of the classical benzodiazepine (BDZ) anxiolytic drug chlordiazepoxide (CDP) and the non-BDZ anxiolytic agent buspirone (BUSP) on basal and stress-induced plasma noradrenaline (NA), adrenaline (A) and corticosterone (CS) release were investigated. Male Wistar rats provided with a permanent heart catheter and a permanent stomach catheter were used. Placement of rats into an unfamilia...

The toroid-shaped nuclear protein export factor CRM1 is constructed from 21 tandem HEAT repeats, each of which contains an inner (B) and outer (A) α-helix joined by loops. Proteins targeted for export have a nuclear export signal (NES) that binds between the A-helices of HEAT repeats 11 and 12 on the outer surface of CRM1. RanGTP binding increases the affinity of CRM1 for NESs. In the absence o...

Owing to its vibration reduction and indirect signal amplification characteristics, a nonlinear energy sink (NES) is used for crack identification of structures. The equation cracked simply supported beam with an NES derived the influences properties on dynamics system are investigated. A pixel method applied estimate phase diagram areas parameters identified based geometric features diagram. I...

This memo de nes an architectural model for active networks. It de nes the assumptions and goals for the active network and describes the functionality of each node. The approach speci es a set of basic functions from which the end-to-end abstractions presented to the user are implemented.

We study the following problem: If ξ1, ξ2, . . . are fuzzy numbers with modal values M1, M2, . . . , then what is the strongest t-norm for which lim n→∞ Nes ( mn − ≤ ξ1 + · · ·+ ξn n ≤ mn + ) = 1, for any > 0, where mn = M1 + · · ·+Mn n , the arithmetic mean ξ1 + · · ·+ ξn n is defined via sup-t-norm convolution and Nes denotes necessity.

The improvement of solubility and/or dissolution rate of poorly soluble natural compounds is an ideal strategy to make them optimal candidates as new potential drugs. Accordingly, the allyl sulfur compounds and omega-3 fatty acids are natural hydrophobic compounds that exhibit two important combined properties: cardiovascular protection and antitumor activity. Here, we have synthesized and char...

Multidrug-resistant Staphylococcus aureus infections pose a significant threat to human health. Antibiotic resistance is most commonly propagated by conjugative plasmids like pLW1043, the first vancomycin-resistant S. aureus vector identified in humans. We present the molecular basis for resistance transmission by the nicking enzyme in S. aureus (NES), which is essential for conjugative transfe...

The Caching pattern describes how to avoid expensive reacquisition of resources by not releasing the resources immediately after their use. The resources retain their identity, are kept in some fast-access storage, and are re-used to avoid having to acquire them again. Note: This pattern appeared in a heavily reworked and updated version in the book Pattern-Oriented Software Architecture — Patt...