BACKGROUND Amnioreduction remains a treatment option for pregnancies with twin-to-twin transfusion syndrome (TTTS) not meeting criteria for laser surgery or those in which it is not feasible. Amnioreduction is a relatively simple treatment which does not require sophisticated technical equipment. Previous reports of conservative management have indicated that major neurodevelopmental impairment...

CONTEXT Neonatal infections are frequent complications of extremely low-birth-weight (ELBW) infants receiving intensive care. OBJECTIVE To determine if neonatal infections in ELBW infants are associated with increased risks of adverse neurodevelopmental and growth sequelae in early childhood. DESIGN, SETTING, AND PARTICIPANTS Infants weighing 401 to 1000 g at birth (born in 1993-2001) were ...

BACKGROUND Newborn animal and human pilot studies suggest that mild hypothermia following peripartum hypoxia-ischaemia in newborn infants may reduce neurological sequelae, without adverse effects. OBJECTIVES To determine whether therapeutic hypothermia in encephalopathic asphyxiated newborn infants reduces mortality and long-term neurodevelopmental disability, without clinically important sid...

Background: Late Preterm (LP) infants, previously considered low risk, have been identified to be at risk of developmental problems in infancy and early childhood. There is limited information on the outcome these infants middle income countries. This study was aimed assess neurodevelopmental status LP born neonates determine factors associated with adverse a tertiary hospital Chattogram, Bangl...

Background: Late-preterm infants (34-36+6 weeks’ gestation) are often believed to have no higher risks for morbidity and mortality than term infants. This study aims to evaluate the neurodevelopmental outcome of late preterm infants at 12 months of age, compared to term infants. Methods: Neurodevelopmental assessment was administered using the Bayley Scale of Infant Development. Eighty particip...

BACKGROUND AND PURPOSE Anomalies associated with callosal agenesis (ACC) found postnatally have been well documented. However, to our knowledge, no detailed MR imaging analysis of associated anomalies has been reported in a large cohort of fetuses with ACC. This study will assess those anomalies and compare them with postnatal cohorts of ACC, to identify associated fetal brain abnormalities tha...

This randomized controlled trial was done to assess whether endotracheal suctioning of nonvigorous infants born through meconium stained amniotic fluid (MSAF) reduces the risk and complications of meconium aspiration syndrome (MAS). Term, nonvigorous babies born through MSAF were randomized to endotracheal suction or no suction groups (n=61 in each). Risks of MAS, complications of MAS and endot...

Candidal meningitis is a serious complication of systemic candidiasis and cause of major morbidity and mortality. This is especially true in very low birth weight premature infants. We describe a premature neonate who suffered from systemic candidal infection with brain parenchymal involvement detected by cranial ultrasound. This patient survived after antifungal treatment but delayed neurodeve...

Posthemorrhagic hydrocephalus (PHH) is a rare but serious outcome among premature babies in the NICU, with consequences including mortality and severe neurodevelopmental disabilities. The causes of PHH are still not entirely understood, and its prevention and treatment are controversial. Various cerebrospinal fluid biomarkers have been studied in infants with PHH in order to recognize the cause...

IMPORTANCE Postnatal dexamethasone is associated with reduction in bronchopulmonary dysplasia. There remains, however, concern that its short-term benefits are accompanied by long-term adverse effects e.g. poorer neurodevelopmental outcomes. OBJECTIVE Our aim was to determine the effects of administration of postnatal dexamethasone on respiratory and neurodevelopmental outcome at two years of...