BACKGROUND Current recommendations on the treatment of neuroendocrine carcinoma of the larynx (NCL) are based on anecdotal evidence. With this meta-analysis, our purpose was to provide clinicians with more substantiated guidelines in order to improve the treatment outcome of the patients affected with NCL. METHODS A structured literature search for all research concerning NCL was performed ag...

The first studies to assess in vitro angiogenesis in neuroendocrine tumors used animal-based assays to study the antiangiogenic properties of somatostatin analogs. Current technologies enable investigators to directly appraise the in vitro angiogenic response of an individual's neuroendocrine tumor with and without potential antiangiogenic reagents. This article describes the evolution of metho...

Neuroendocrine carcinomas have become increasingly recognized as more reports are emerging to describe these rare tumors. Primary sites include the lung, liver, throat, and other organs. Laryngeal neuroendocrine carcinomas are relatively rare, and the subtypes as well as the prognoses are quite different in most cases. Metastases to the liver, lungs and other parts are common. However, metastas...

Prader–Willi syndrome (PWS) is a neuroendocrine genetic disorder resulting from the loss of paternally expressed imprinted genes in chromosome 15q11-q13 [...]

BACKGROUND Osmotic and neural factors stimulate neuroendocrine activity during exercise. In contrast to excitatory mechanisms, afferent information from cardiac mechanoreceptors inhibits integrative centers in the hypothalamus and medula oblongata, which serves to buffer neuroendocrine activity. Orthotopic cardiac transplantation results in the loss of afferent information from cardiac mechanor...

The neuroendocrine system, which plays an integral role in regulation of mood, is dysfunctional in patients with affective disorders. This paper reviews data from anatomic, functional, and clinical studies elucidating neuroendocrine function in patients with bipolar disorder. In an anatomic study using magnetic resonance imaging, patients with bipolar disorder had significantly smaller pituitar...