BACKGROUND AND AIMS Wilson disease (WD) is an inherited disorder of copper metabolism, and an international group for the study of WD (IGSW) has proposed three phenotypes for its initial presentation: acute hepatic, chronic hepatic, and neurologic phenotypes. Characterization of the acute hepatic phenotype may improve our understanding of the disease. METHODS Clinical features of 10 WD patien...

INADEQUATE/INSUFFICIENT EVIDENCE TO DETERMINE WHETHER AN ASSOCIATION EXISTS • Any cancer • Cardiovascular conditions or conditions of the blood and blood-forming organs • Endocrine, nutritional, and metabolic conditions • Neurodegenerative diseases other than ALS and multiple sclerosis • Neurocognitive and neurobehavioral performance • Migraines and other headache disorders • Other neurologic o...

The cerebrospinal fluid (CSF) IgG index, the CSF to serum albumin ratio, and electrophoresis on agarose gel of CSF and serum were evaluated retrospectively for their usefulness in the differential diagnosis of multiple sclerosis (MS). Standardized procedures were adopted for grading the intensity of oligoclonal banding and for the certainty of diagnosis of MS. One hundred and forty-nine patient...

background: because of the ability of proliferation, regeneration, conversion to differentiated cells and tissue producing, stem cell therapy has important clinical implications for treatment of different diseases. in this chapter we discuss different kinds of stem cells that have been used in treatment of neurologic diseases, gastrointestinal diseases, heart diseases, bone disease, kidney dise...

Allogeneic hematopoietic stem cell transplantation (HSCT) is the only curative treatment for Griscelli syndrome type 2, an inherited immune disorder causing fatal hemophagocytic lymphohistiocytosis (HLH). Optimal therapeutic modalities are not yet well known. We retrospectively analyzed the outcome for 10 patients who underwent HSCT in a single center between 1996 and 2008. Seven patients (70%)...

A survey was developed to examine the perception of equine practitioners regarding the occurrence of five equine neurologic diseases in the northeastern United States over the 10-year period between June 1, 1997 and June 1, 2007. This information was then compared with trends at Cornell University’s Equine Hospital during the same time span, which ingeneral agreed with practitioners’ opinions. ...