نتایج جستجو برای: neurometabolic disorder

تعداد نتایج: 597203  

Journal: :The Journal of neuroscience : the official journal of the Society for Neuroscience 2007
Baowang Li Ralph D Freeman

The relationships between neural and metabolic processes in activated brain regions are central to the interpretation of noninvasive imaging. To examine this relationship, we have used a specialized sensor to measure simultaneously tissue oxygen changes and neural activity in colocalized regions of the cat's lateral geniculate nucleus (LGN). Previous work with this sensor has shown that a decre...

2017
Ali G. Hamedani Daniel R. Gold

Eye movement abnormalities are among the earliest clinical manifestations of inherited and acquired neurodegenerative diseases and play an integral role in their diagnosis. Eyelid movement is neuroanatomically linked to eye movement, and thus eyelid dysfunction can also be a distinguishing feature of neurodegenerative disease and complements eye movement abnormalities in helping us to understan...

Journal: :Stroke 2002
Michael D Hill Philip A Barber Andrew M Demchuk Nancy J Newcommon Andrea Cole-Haskayne Karla Ryckborst Laurel Sopher Allison Button William Hu Mark E Hudon William Morrish Richard Frayne Robert J Sevick Alastair M Buchan

BACKGROUND Intravenous alteplase for acute ischemic stroke is least efficacious for patients with proximal large-artery occlusions and clinically severe strokes. Intra-arterial therapy has the theoretical advantage of establishing a neurovascular diagnosis and high symptomatic artery patency rate but the disadvantage of requiring extra time and technical expertise. A combination of these two ap...

2014
Parveneh KARIMZADEH Farzad AHMADABADI Narjes JAFARI Fakhreddin SHARIATMADARI Hamid NEMATI Adel AHADI Sanaz KARIMI DARDASHTI Mehrdad MIRZARAHIMI Zahra DASTBORHAN Javad ZARE NOGHABI

OBJECTIVE Phenylketonuria is one of the most common metabolic disorders and the first known cause of mental retardation in pediatrics. As Screening for phenylketonuria (PKU) is not a routine neurometabolic screening test for neonates in Iran, many PKU cases may be diagnosed after developing the clinical symptoms. One of the findings of PKU is myelination disorders, which is seen as hypersignal ...

2013
Jillian L. Stobart Christopher M. Anderson

Dynamic adjustments to neuronal energy supply in response to synaptic activity are critical for neuronal function. Glial cells known as astrocytes have processes that ensheath most central synapses and express G-protein-coupled neurotransmitter receptors and transporters that respond to neuronal activity. Astrocytes also release substrates for neuronal oxidative phosphorylation and have process...

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