Nuclear weapons are popularly regarded as the horror of the twentieth century. Yet, many argue that they promoted peace through the cold war. To examine the effect of nuclear weapons on international politics, this essay explores how nuclear arsenals could have stopped WWII or made it all the more horrifying. This essay first explains the relevant understanding of the use of nuclear force. It t...

The Netherlands and other northern European countries have been enduring leaders in methicillin-resistant Staphylococcus aureus (MRSA) control across hospital and community environments. When I spoke to a Dutch colleague about their secret, I heard that some twenty-five years ago, when MRSA was starting to be seen in Europe, the microbiologists from across the country got together and in a reso...

PURPOSE Rhabdomyosarcoma (RMS) is a soft tissue sarcoma associated with the skeletal muscle lineage. Of the two predominant subtypes, known as embryonal (eRMS) and alveolar (aRMS), aRMS has the poorer prognosis, with a five-year survival rate of <50%. The majority of aRMS tumors express the fusion protein PAX3-FOXO1. As PAX3-FOXO1 has proven chemically intractable, this study aims to identify t...

Due to structural complexity of robot arms, constraints experiments, especially uncertainty design parameters, numerical models for dynamics analysis arms can produce erroneous results, which seriously affect the performance designed arms. Reliable parameter identification becomes important. The current methods have double-layered processes, in inner layer is propagation and outer an iterative ...

jak2 is a tyrosine kinase that plays an important role in the signaling pathways of many hematopoietic growth factor receptors. a single acquired point mutation – v617f – in jak2 occurs in the great majority of patients with polycythemia vera (pv) and approximately half of the patients with idiopathic myelofibrosis (imf) or essential thrombocythemia (et). in contrast, the jak2-v617f mutation is...

background & aim : mother-infant separation is one of the main causes of sleep-wake states disorders in neonatal intensive care unit (nicu). the current study was conducted to investigate the effect of in-arms-holding by mothers on sleep-wake states disorders of preterm neonates. methods & materials : in a pilot study, through a semi-experimental pretest-posttest method, 35 preterm neonates wit...