Hexane extract of the seeds of Nigella sativa L. prevented pregnancy in Sprague-Dawley rats treated orally at 2 g/kg daily dose on days 1-10 post-coitum. Significant antifertility activity was also observed in its column fractions and subfractions. At contraceptive dose, the active hexane extract exhibited only mild uterotrophic activity comparable almost to 0.002 mg/kg dose of 17 varies; is di...

OBJECTIVE To study the potential efficacy and tolerability of a natural multiherbal formula (Immumax) containing Echinacea extract 120 mg, garlic powder 100 mg, Nigella sativa oil 200 mg, and Panax ginseng extract 50 mg plus vitamin C 50 mg and elemental zinc 7.5 mg in the treatment of patients suffering from the common cold. DESIGN AND SETTING The study was conducted in a prospective, double...

Lipídeos inéditos foram isolados de matéria insaponificável extraída de sementes de Nigella sativa Linn, usando-se n-hexano. O dienoato e os dois monoésteres inéditos foram identificados por técnicas espectrométricas, incluindo IV, RMN de H e C, espectrometria de massas, e análise química. O dienoato (1) foi identificado como metilnonadeca-15, 17-dienoato e os dois monoésteres foram identificad...

The effect of aqueous extract of Allium sativum on phospatases activity in albino rats was investigated. Twelve rats were randomly grouped into four where rats in B, C and D groups were treated daily with oral administration of aqueous extract of Allium sativum at 50mg/kg, 100mg/kg and 150mg/kg body weight respectively for two weeks. The control group A received no treatment. The results showed...

Pisum sativum (Family: Fabaceae), as known as green pea or garden pea, has long been important in diet due to its content of fiber, protein, starch, trace elements, and many phytochemical substances. It has been shown to possess antibacterial, antidiabetic, antifungal, anti-inflammatory, antihypercholesterolemia, and antioxidant activities and also shown anticancer property. Its nonnutritive bi...

BACKGROUND The present paper describes the isolation and characterization of two new aliphatic δ-lactones along with three glycerides and n-nonadecanyl cetoleate from the fruits of Coriandrum sativum L. (Apiaceae). The structures of all the isolated phytoconstituents have been established on the basis of spectral data analysis and chemical reactions. RESULTS Phytochemical investigation of the...

in the previous studies the relaxant, anti-cholinergic (functional antagonism) and anti-histaminic effects of nigella sativa have been demonstrated on guinea pig tracheal chains. to elucidate the main substance responsible for the relaxant effect of this plant, the effect of thymoquinone, one of the main constituent of nigella sativa was examined in this study. the bronchodilatory effects of th...

BACKGROUND Garlic is considered a rich source of many compounds, which shows antimicrobial effects. The ability of microorganisms to adhere to both biotic and abiotic surfaces and to form biofilm is responsible for a number of diseases of chronic nature, demonstrating extremely high resistance to antibiotics. Bacterial biofilms are complex communities of sessile microorganisms, embedded in an e...

AIM OF THE STUDY To provide ethnopharmacological basis for the medicinal use of Lepidium sativum seeds in indigestion and constipation. MATERIALS AND METHODS The in vivo studies were conducted in mice, while isolated tissues of mouse, guinea-pig and rabbit were suspended in tissue bath to measure isotonic contractions. RESULTS The aqueous-methanolic extract of Lepidium sativum seeds (Ls.Cr)...