Dental professionals are required to wear gloves for all treatments. Most wear natural rubber latex gloves. This may cause sensitization to latex proteins and subsequent allergic reactions (1). We report the case of a 21-year-old dental undergraduate student who, after the first time he had worn latex gloves during a practical session in the second year of his course, developed severe allergic ...

An efficient synthesis of a range of 1,2-benzisoxazoles using an improved 1,3-dipolar cycloaddition of nitrile oxides and benzyne is described. Key to the procedure is the in situ generation of the reactive nitrile oxide and benzyne reaction partners mediated by TBAF. Reactions are complete within 30 s, giving the target products in good to excellent yield.

The objective of this study was to quantify the colony forming units (cfu) on latex procedure gloves in the beginning, middle, and end of the containers in real (professional) and controlled (researcher) gloving situations; evaluate the microbial load of the gloves, considering the time of exposure in the environment. This comparative prospective study was conducted at an intensive care unit of...

BACKGROUND Natural rubber latex (NRL) allergy is a common occupational disease in health care workers (HCW). However, few reports have compared the major allergen of HCWs to those in gloves that are routinely used in the hospital. The aim of this study was to evaluate the major NRL allergens in gloves used by HCWs. METHODS We studied 20 HCWs who were suspected to have latex allergy (LA). We p...

Nitrile hydratases (NHases) are mononuclear nonheme enzymes that catalyze the hydration of nitriles to amides. NHase is unusual in that it utilizes a low-spin (LS) FeIII center and a unique ligand set comprised of two deprotonated backbone amides, cysteine-based sulfenic acid (RSO(H)) and sulfinic acid (RSO2-), and an unmodified cysteine trans to an exogenous ligand site. Electron paramagnetic ...

r o he early story of the use of gloves by surgeons and obstericians has been well documented by Randers-Pehrson nd by Miller. Walbaum, in 1758, used the cecum of the heep as a partial hand covering in his obstetric practice, nd gloves made successively of cotton, silk, leather, and inally rubber were used in the 19 century. Rubber beoming the material of choice after Charles Goodyear deeloped ...

BACKGROUND In a follow-up to a previous article, which described the approach at The Johns Hopkins Medical Institutions to establishing a latex-safe environment, subsequent efforts to convert all the sterile gloves to nonlatex products and thereby complete the implementation of a latex-safe program are reported. Before the complete conversion to nonlatex sterile gloves, operating room use had i...

Sterile radiation reduction gloves have been widely used over the past several decades in an effort to reduce hand doses during fluoroscopically guided proce- dures. While multiple studies have quantified the potential dose reduction to the fluoroscope operator from the use of such gloves, possible effects on the patient have not yet been quantified. The aim of this study was to examine the imp...