PURPOSE A recent study demonstrated improvement in nocturnal urgency in patients with overactive bladder when treated with fesoterodine. In the current study we aimed to determine which bladder diary parameters predict the response to fesoterodine in these patients. MATERIALS AND METHODS Patients with nocturnal urgency completed a 2-week, single-blind placebo run-in followed by 1:1 double-bli...

OBJECTIVES Our objectives were to study the temporal correlation of physical activity time series in patients with chronic fatigue syndrome (CFS) during normal daily life and to examine if it could identify the altered physical activity in these patients. METHODS Fractal scaling exponents of diurnal and nocturnal physical activity time series in 10 CFS patients and 6 healthy control subjects ...

OBJECTIVE To determine the effect of nocturnal hypoglycaemia on sleep architecture in adolescents with insulin dependent diabetes mellitus (IDDM). DESIGN 20 adolescents with IDDM (mean age 12.8 years, mean glycated haemoglobin (HbA1c) 8.9%) were studied on one night. Plasma glucose was measured every 30 minutes and cortisol and growth hormone levels every 60 minutes. Sleep was recorded using ...

Are there really nocturnal bees? Surprisingly, yes. Most people, if asked about bees, think of those industrious dayactive species, like the common honeybee, that harvest sunny meadows of flowers for pollen and nectar. And such images are not misguided — most bees are indeed day active (diurnal). By sundown most bees are safely back in the nest, their day’s labours complete. But for some bees, ...

Lifestyle and heredity are two different terms but yet closely related components. An evaluation for the time invested in sleep locomotion behaviors per second Wistar rats animal model was carried out. A total of six within same cage were marked by color a room supported day’s light (12h lighting/12h darkness). These animals filmed 18 h daily ten days (9h lighting, 9h darkness) to estimate budg...

This study was designed to evaluate the performance of movement detectors (pedometers) in measuring daily activity of patients with chronic lung disease. Three groups of subjects were studied: group 1: 25 patients with stable nonhypercapnic chronic obstructive pulmonary disease (COPD) (forced expiratory volume in one second (FEV1) = 47+/-9% predicted) studied twice, one month apart; group 2: 25...

The Lesotho mole-rat is a social subterranean rodent that occurs at altitude in the Drakensberg mountain range. As a consequence of living permanently underground these animals rarely if ever are exposed to light. The visual system of African mole-rats is particularly regressed whereas the circadian system is proportionately conserved. This study investigated the locomotor activity patterns of ...