We have developed two analytical models to describe the performance of cryogenic microcalorimeters and bolometers. One of the models is suitable to describe Transition Edge Sensor(TES) detectors with an integrated absorber, the other is suitable for detectors with large absorbers. Both models take into account hotelectron decoupling and absorber decoupling. The differential equations describing...

1. Inhibition of neutral endopeptidase (NEP), the degradative enzyme for atrial natriuretic peptide, was studied in vitro and in vivo using a previously characterized NEP inhibitor radioligand, 125I-labelled RB104. 2. SCH 42354, the active di-acid of the ethylester prodrug, SCH 42495, caused a concentration-dependent displacement of 125I-labelled RB104 from rat renal NEP. The concentration of S...

the aim of the present study was to examine the rate of noise induced hearing loss in a group of punching and cutting section and other occupational groups workers and its relation with sound pressure levels, age and work history. this descriptive, cross-sectional study included 245 workers of the punching and cutting section and other occupational groups of an iranian axial parts factory in 20...

a complete procedure for the design of w-band low noise amplifier in mmic technology is presented. the design is based on a simultaneously power and noise matched technique. for implementing the method, scalable bilateral transistor model parameters should be first extracted. the model is also used for transmission line utilized in the amplifier circuit. in the presented method, input/output ma...

purpose: to evaluate the role of active uveitis on refractive errors changes. methods: a cohort single group study was conducted on patients with acute or recurrent uveitis. cyclorefraction was performed in both phases of active and quiescent. sphere, cylinder and sphere equivalent power were compared in active and quiescent phases and analyzed statistically. results: sixty-six patients (eighty...

Neutral endopeptidase (NEP; CALLA, CD10, EC 3.4.24.11) is a cell surface endopeptidase that hydrolyses bioactive peptides, including the bombesin-like peptides, as well as other neuropeptides. Bombesin-like peptides and other neuropeptides are autocrine growth factors for both small cell lung cancer (SCLC) and non-small cell lung cancer (NSCLC). Low expression of NEP has been reported in SCLC a...

BACKGROUND The study aimed to evaluate health care resource utilization (HRU) and costs for neuropathic pain (NeP) secondary to spinal cord injury (SCI) among Medicaid beneficiaries. METHODS The retrospective longitudinal cohort study used Medicaid beneficiary claims with SCI and evidence of NeP (SCI-NeP cohort) matched with a cohort without NeP (SCI-only cohort). Patients had continuous Medi...

Substance P (SP) is well known to promote inflammation in acute pancreatitis (AP) by interacting with neurokinin-1 receptor. However, mechanisms that terminate SP-mediated responses are unclear. Neutral endopeptidase (NEP) is a cell-surface enzyme that degrades SP in the extracellular fluid. In this study, we examined the expression and the role of NEP in caerulein-induced AP. Male BALB/c mice ...

OBJECTIVE Neuropeptides from nerve fibres can cause neurogenic inflammation. The potency of these peptides in vitro has led to the hypothesis that enzyme degradative systems are operative in vivo to limit their action. To consider this question neutral endopeptidase (NEP) in labial salivary glands in patients with Sjögren's syndrome was studied. METHODS Synthesis of NEP mRNA in situ in labial...