Hormonal levels are the hallmark for assessment of testicular function in XY DSD (Disorders sex development). Traditionally, it has relied on testosterone level increment after hCG (human Chorionic Gonadotropin) stimulation testing. More recently role Sertoli cell hormones is more emphasized. Objectives: Evaluating serum anti-mullerian hormone and inhibin B pre-pubertal testis without need test...

BACKGROUND Clomiphene citrate (CC) response in anovulatory women is difficult to predict and patient-tailored treatment would benefit patient care and time-management. The objective of this study was to evaluate the role of the follicle-stimulating hormone receptor (FSHR) Ser680Ser-polymorphism as a predictor for CC response. METHODS In this retrospective study, 193 patients, diagnosed with p...

Gonadotropins, follicle-stimulating hormone (FSH) and luteinizing hormone (LH) have been implicated as probable risk factors in epithelial ovarian carcinomas, most of which are derived from ovarian surface epithelium (OSE). Since epidermal growth factor (EGF) increases the growth of ovarian surface epithelial cells, we determined the effect of gonadotropins on the expression of epidermal growth...

Premature menopause and unexplained infertility are associated with ovarian antibodies, a marker of ovarian autoimmunity. In premature menopause, FSH is also elevated while in unexplained infertility FSH concentrations are often normal. The relationship of ovarian antibodies and FSH and inhibin B, as markers of follicle function, was investigated in unexplained infertility. Ovarian antibodies w...

Recent studies suggest that bone marrow stem cells (BMSCs) are promising grafts to treat a variety of diseases, including reproductive dysfunction. Primary ovarian failure is characterized by amenorrhea and infertility in a normal karyotype female, with an elevated serum level of follicle-stimulating hormone (FSH) and a decrease level of estrogen caused by a mutation in FSH receptor (FSHR) gene...

OBJECTIVE To examine whether obesity and insulin resistance have an independent effect on the gonadotropin, estradiol, and inhibin B serum levels and follicle count in the early follicular phase of fertile women with a wide range of BMI and without signs of hyperandrogenism. RESEARCH METHODS AND PROCEDURES Twenty-two overweight and obese (BMI > or =25.0 kg/m(2)) women and 10 normal-weight (BM...

The aim of the current study to determine levels Inhibin-B hormone and its relationship with some gonadal hormones, including follicle-stimulating (FSH), luteinizing (LH) prolactin, testosterone hormones in males idiopathic infertility Shirqat city.
 Blood seminal fluid samples from (60) male infertile (30) healthful individuals as (control group) aged (18 60 years) were collected private ...

INTRODUCTION Anti-Müllerian hormone represents the primitive follicular number and ovarian age. Low level of AMH is in relation to early menopausal state and decreased ovarian reserve. AMH level changes occur prior to FSH level in representing ovarian failure. The aim of this study is to compare sensitivity and specificity of AMH with FSH in diagnosis of POF. MATERIAL AND METHODS This descrip...

Background: Azoospermia is the total absence of sperm cells from a patients semen sample after centrifugation. It could be obstructive or non-obstructive and its associated causes include chromosomal defects, infections, gonadotrophins imbalance, and etc in the patients. The objective is to determine the prevalence of primary testicular failure, germinal insufficiency, obstructive azoospermia a...