نتایج جستجو برای: nuclear factor κ b nfκ b
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For cardinals κ, λ,μ we let bκ,λ,μ be the smallest size of a subset B of λμ unbounded in the sense of ≤κ ; that is, such that there is no function f ∈ λμ such that {α < λ : g(α) > f (α)} has size less than κ for all g ∈ B. Similarly for dκ,λ,μ, the general dominating number, which is the smallest size of a subset B of λμ such that for every g ∈ λμ there is an f ∈ B such that the above set has s...
Our previous studies have demonstrated that the effects of the immune cytokine interferon-γ (IFN-γ) in immune-mediated demyelinating diseases are mediated, at least in part, by the unfolded protein response (UPR) in oligodendrocytes. Data indicate that some biological effects of IFN-γ are elicited through activation of the transcription factor nuclear factor-κB (NF-κB). Interestingly, it has be...
OBJECTIVES To assess activation of the inflammatory transcription factor NF-kappa B (NF-κB) in human idiopathic pulmonary arterial hypertension (PAH). BACKGROUND Idiopathic PAH is a severe progressive disease characterized by pulmonary vascular remodeling and excessive proliferation of vascular cells. Increasing evidence indicates that inflammation is important in disease pathophysiology. M...
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