To the Editor: Dr Flegal and colleagues concluded that grade 1 obesity was not associated with higher all-cause mortality and that overweight was associated with significantly lower all-cause mortality. Other studies have shown that obesity in different populations, such as elderly people and patients with cardiovascular diseases, is also paradoxically not associated with a higher but rather wi...

BACKGROUND Obesity, defined by body mass index (BMI), appears to have a paradoxical protective effect in several chronic diseases. OBJECTIVE We investigated the obesity paradox in cancer patients by using body composition. DESIGN The study was an observational study of 175 cancer patients assessed before chemotherapy. Obesity was defined as BMI (in kg/m(2)) ≥30 or fat mass index (FMI; fat m...

Abstract Background Obesity is a well-established risk factor for type 2 diabetes mellitus, hypertension and dyslipidemia, leading to coronary artery disease (CAD). Nevertheless, body mass index (BMI) inversely associated with cardiovascular (CV) mortality in patients cardiac disorders, termed “obesity paradox”. However, the underlying mechanism remains unclear. Purpose To clarify important fac...

In hemodialysis patients, lower body mass index and weight loss have been associated with higher mortality rates, a phenomenon sometimes called the obesity paradox. This apparent paradox might be explained by loss of muscle mass. The authors thus examined the relation to mortality of changes in dry weight and changes in serum creatinine levels (a muscle-mass surrogate) in a cohort of 121,762 he...

Background: Recent studies have shown that cancer patients with low BMI poor outcomes. Their results suggest, obesity some protective effect in termed as “obesity paradox”. Aim: To examine the association of prognostic indicators oral squamous cell carcinoma (OSCC). Methodology: This multicenter cross-sectional study was conducted during year 2020 and 2021. 126 recently diagnosed OSCC were rand...