Ara-A ointment was compared to IDU ointment in patients with dendritic herpes simplex virus infection of the corneal epithelium. Twenty-eight patients were treated with Ara-A ointment and twenty-four with IDU ointment. The lesions healed in 5.1 days with Ara-A and in 6.9 days with IDU. This drug was given in a double-controlled manner, so that neither the patient, nor the investigator knew whic...

A general scheme to aid in the selection of therapies is described A topological sorting procedure within a general production rule representation is introduced The procedure is used to choose among competing therapies on the basis of precedence rules This approach has a degree of naturalness that lends itself to automatic explanation of the choices made A system has been implemented using this...

Swabbings from the eyes of 4132 patients attending ophthalmic casualty and outpatients clinics were tested for chlamydiae, adenovirus, and herpes simplex virus. Laboratory isolation tests gave positive results for one of these three agents in 696 (16.8%) cases. When a positive isolation was obtained, only 341 (49%) agreed with the clinical diagnosis while 355 (51%) either had no definite diagno...

Kirwan, E. O'G.-" Epidemic Superficial Punctate Keratitis in Bengal." Prcc. All-India Obhthal. Soc., Vol. III, p. 1, 1933. Kuchner, K.-" Inoculations with Herpes Virus." Klin. Monatsbl. f. A tgenheilk., Vol. XCI, p. 485, 1933. Lloyd, R. I.-" Herpes and Allied Conditions." Amer. Ji. of Ophthal., Vol. XIV, p. 601, 1931. Moore, R. F -" Ocular Manifestations of Lesions of the Fifth Nerve." British ...

PURPOSE Herpes simplex virus type I (HSV-1) is capable of causing a wide array of human ocular diseases. Herpes simplex virus keratitis (HSK)-induced cytopathogenicity together with the chronic immune-inflammatory reaction can trigger stromal scarring, thinning, and neovascularization which may lead to permanent vision impairment. Lychee flower extract (LFE) is known for its antioxidant and ant...

A 71-year-old man presented with herpes zoster ophthalmicus and ocular involvement. Following the institution of intravenous therapy with acyclovir, the patient developed fever, hemoptysis, and a pleural friction rub. A ventilation-perfusion lung scan showed no defects; roentgenograms showed bilateral infiltrates and a left-sided pleural effusion. The fever abated promptly following discontinua...

A clinical isolate of type I Herpes virus was injected intracerebrally in 4-week-old Balb/C mice. Bilateral ocular disease was observed initially clinically as a leukocoria and an anterior uveitis on the 7th to 11th postinjection days. By day 21 an organized vascularized retrolental membrane had formed with resolution of active inflammation and secondary cataract formation. Light microscopy rev...

Five hundred specimens (288 genital, 192 dermal, and 20 ocular) were extracted by technologists, and the DNA was assayed by LightCycler PCR (DNA polymerase and thymidine kinase [TK] gene targets) and by conventional tube and shell vial cell culture. One hundred fifty-eight confirmed (by cell culture and TK target PCR) positive and LightCycler-positive specimens were detected during the first 30...

Since 1968, I have been providing relief in 30 min for patients with acute influenza, as well as for patients with all five types of herpes virus infection seen in my practice. Relief occurs more rapidly than from any antibiotic or anti-viral treatment available. This remarkable response has been obtained by subcutaneously injecting a small skin test determined dose of ordinary influenza virus ...