BACKGROUND Compared with the general population, cancer patients have a higher risk of venous thromboembolism as well as arterial thrombotic events such as stroke, myocardial infarction and peripheral arterial embolism. Therefore a possible concern for women with malignancies undergoing ovarian stimulation for fertility preservation is the increased risk of venous or arterial thrombosis. METH...

Ovarian hyperstimulation syndrome (OHSS) is the price patients pay for our attempt to override nature’s delicate balances that were created to assure a single oocyte ovulation. Spontaneous OHSS does occur, as we delineate later. It is, however, very rare. Indeed, natural-cycle-based assisted reproductive technologies (ART) were responsible for the birth of the first IVF baby; however, this meth...

OBJECTIVE To determine if the GnRH antagonist protocol is effective in preventing ovarian hyperstimulation syndrome (OHSS) in potentially high responders. METHODS A total of 660 IVF-ET/ICSI cycles were retrospectively identified. The inclusion criterion was age ≤ 30 years. Cycles were divided into two groups: a GnRHa group and a GnRHant group. In the GnRHa group, the patients received one sin...

Gonadotropin-releasing hormone agonists (GnRHa) have gained increasing attention in the last decade as an alternative trigger for oocyte maturation in patients at high risk for ovarian hyperstimulation syndrome (OHSS). They provide a short luteinizing hormone (LH) peak that limits the production of vascular endothelial growth factor, which is the key mediator leading to increased vascular perme...

BACKGROUND Ovarian stimulation in IVF cycle results in luteal supraphysiological steroid concentrations especially for high response patients. The aim of this study was to evaluate the efficacy of ovarian steroid hormone suppression in luteal phase after oocyte retrieval for preventing severe ovarian hyperstimulation syndrome (OHSS) in high-risk patients with embryo cryopreservation. METHODS ...

Multiple pregnancies and ovarian hyper stimulation syndrome (OHSS) are the most serious complications of ovarian stimulation and IVF. Indeed, they are more or less the only ones. OHSS can effectively be prevented in three stages: Before stimulation, during stimulation and at ET. Before stimulation patients should be assessed as to age, the ovarian follicular count and/or anti mullerian hormone ...

BACKGROUND AND PURPOSE In-hospital strokes (IHSs) are potential candidates for thrombolysis. We analyzed the treatment procedures, safety, and efficacy of intravenous tissue plasminogen activator (IV-tPA) in IHSs compared with out-of-hospital strokes (OHSs). METHODS This study was based on a multicenter prospective registry of patients treated with IV-tPA divided into IHSs and OHSs. We record...

Assisted reproductive techniques (ART) are elective procedures in otherwise healthy patients. Therefore any complication occurring during treatment is iatrogenic. Sadly, the most serious and potentially life threatening complication, the ovarian hyperstimulation syndrome (OHSS) still frequently occurs. Abramov et al. (1999) report an increase in the incidence of OHSS and state that we are facin...

In a prospective randomized study, we analysed 125 patients at risk of ovarian hyperstimulation syndrome (OHSS), selected in the period between January 1996 and July 1997. All the patients had blood oestradiol concentration >/=1500 pg/ml on the day of human chorionic gonadotrophin (HCG) administration and >/=15 oocytes were collected. The patients were matched in two groups: group A, control gr...