Hippophae rhamnoides L. (Elaeagnaceae) is a hardy, deciduous shrub with yellow or orange berries. H. rhamnoides contains a series of chemical compounds including flavonols, sterols, lipids, triterpenoids, etc. H. rhamnoides has been used as a traditional medicine for the treatment of cough, indigestion, and blood stasis in China. Macrophages play major roles in host defense, immunity, and infla...

Oleanolic acid (OA) is a pentacyclic triterpenoid widely found in plants and foods as an aglycone of saponins or free acid. OA exhibits beneficial activities for humans, including antitumor, antivirus, hepatoprotection properties without apparent toxicity. The metabolites produced by the cytochrome P450 (P450) enzymes are critical evaluation efficacy safety drugs. In this study, potential were ...

Nowadays, COVID-19 cases are growing worldwide, and there is no evidence of an effective drug to combat the new SARS-CoV-2 virus. In this sense, medicinal plants as alternative treatment being used without control handle pandemic situation. Therefore, bioactive compounds against Coronavirus plant species that grow in Ecuador discussed. The described review Azadirachta indica, Cinchona pubescens...

From the 1-BuOH-soluble fraction of a MeOH extract of leaves of Schefflera arboricola, collected in Okinawa, six new lupane glucosides, named schefflerins A-F (1-6) and one new dammarane glucoside, named schefflerin G (7), were isolated together with three known compounds, citroside A (8), and oleanane saponins, oleanolic acid (9) and echinocystic acid (10) 3-O-α-L-rhamnopyranosyl(1→4')-O-β-D-g...

Oleanolic acid (OA) and ursolic acid (UA) are important bioactive components in many plants, including persimmon (Diospyros kaki L.). The present work was carried out to determine OA and UA contents in the flesh of persimmon fruit from 32 cultivars, including 23 astringent and 9 non-astringent ones, by applying high performance liquid chromatography (HPLC) with UV detection. Both OA and UA were...

Four sesquiterpenes, beta-selinene, isocurcumenol, nootkatone and aristolone and one triterpene, oleanolic acid were isolated from the ethylacetate fraction of the rhizomes of Cyperus rotundus and tested for their ability to modulate gamma-aminobutyric acid (GABA(A))-benzodiazepine receptor function by radioligand binding assays using rat cerebrocortical membranes. Among these compounds, only i...

Herbal medicines or natural products and plant extract may exhibit promising alternatives supplements for chemotherapy antibiotic therapy. The aim of the study is to evaluate therapeutic value phytoconstituents whole plant, Nepeta distans. methanol contains four known compounds, namely, oleanolic acid, ursolic β-sitosterol, stigmasterol. structures these compounds were confirmed with help NMR m...

In order to develop potential anti-fungal agents, seven glycoconjugates composed of α-L-rhamnose, 6-deoxy-α-L-talose, β-D-galactose, α-D-mannose, β-D-xylose-(1→4)-6-deoxy-α-L-talose, β-D-galactose-(1→4)-α-L-rhamnose, β-D-galactose-(1→3)-β-D-xylose-(1→4)-6-deoxy-α-L-talose as the glycone and oleanolic acid as the aglycone were synthesized in an efficient and practical way using glycosyl trichlor...