نتایج جستجو برای: onset breast cancer
تعداد نتایج: 1152830 فیلتر نتایج به سال:
Background : After lung cancer, breast cancer is the second cause of mortality among women. Although the prevalence of this disease has been increased, but the rate of mortality has not been changed during last three decades, this may be due to early diagnosis at the first stage of disease . Objective : To determine risk factors of breast cancer in women. Design : It was a case- control s...
In this paper we develop a model and a deconvolution technique to estimate the distribution of the age of onset of detectable preclinical cancer, using incidence data and information about cancer growth rate. Our approach considers the e ect of age on both the growth rate and competing causes of death. We illustrate our methodology using data on breast cancer, and discuss implications for breas...
Introduction: Breast cancer is a cancer that is caused by abnormal growth of breast cells. Modeling and simulation of the growth and treatment of breast cancer, along with providing the possibility of doing experiments and research, can reduce the time and cost of treatment by predicting some cases. The purpose of the present research was to develop an agent-based model for the simulation of b...
breast cancer is the most common cancer in women worldwide. breast cancer in one third of all patients will go on to metastasis, which is the main cause of mortality in cancer cases. tumor cells detach from primary tumor and enter into the circulation as circulating tumor cells (ctcs) which can form metastatic lesions. in this study, the expression of ck-19 gene in blood samples of metastatic b...
Introduction: Breast cancer is one the most common form of cancer in women all over the world. The incidence of women breast cancer is increasing in Iran. There are many risk factors involved in the risk of breast cancer so that these risk factors have been determined based on genetic, environmental, and geographical conditions in various studies. The current study aimed to evaluate the risk fa...
Introduction: Breast cancer is a cancer that is caused by abnormal growth of breast cells. Modeling and simulation of the growth and treatment of breast cancer, along with providing the possibility of doing experiments and research, can reduce the time and cost of treatment by predicting some cases. The purpose of the present research was to develop an agent-based model for the simulation of b...
PURPOSE The recognition of breast cancer as a spectrum tumor in Lynch syndrome remains controversial. The aim of this study was to explore features of breast cancers arising in Lynch syndrome families. EXPERIMENTAL DESIGN This observational study involved 107 cases of breast cancer identified from the Colorectal Cancer Family Registry (Colon CFR) from 90 families in which (a) both breast and ...
Introduction: Breast cancer is the most common cancer and cause of cancer-related death in women. Recent years have witnessed dramatic changes in the incidence and mortality rates of breast cancer. Therefore, this study aimed to provide a report of breast cancer incidence trends between 2003 and 2017. Methods: This cross-sectional study examined Iran’s cancer registry reports from 2003 to 2017...
Germline mutations in the human breast cancer genes BRCA1 and BRCA2 account for a substantial proportion of familial, early-onset breast and ovarian cancers. The present study reports a novel disease-causing BRCA1 mutation, nucleotide 3020insCT/c.2901insCT, in a 55-year-old Spanish female with breast and ovarian cancer. This frameshift mutation creates a premature stop codon at amino acid 1000,...
background: breast cancer is the malignancy in humans and other mammals. several risk factors are involved in their appearance such as higher hormone levels and obesity. identification of a mouse mammary tumor virus supports a viral etiology for breast tumors in animals. viruses have been implicated in the development of various cancers, but viral induction for formation breast cancer is contro...
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